Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Estazolam
Drug ID BADD_D00819
Description A benzodiazepine with anticonvulsant, hypnotic, and muscle relaxant properties. It has been shown in some cases to be more potent than diazepam or nitrazepam.
Indications and Usage For the short-term management of insomnia characterized by difficulty in falling asleep, frequent nocturnal awakenings, and/or early morning awakenings.
Marketing Status Prescription; Discontinued
ATC Code N05CD04
DrugBank ID DB01215
KEGG ID D00311
MeSH ID D004949
PubChem ID 3261
TTD Drug ID D0P2CK
NDC Product Code 0591-0744; 51862-074; 12828-0077; 51862-069; 0591-0745; 70954-480; 70954-481; 51862-073; 51862-070; 48087-0031
Synonyms Estazolam | Tasedan | ProSom | D-40TA | D40TA | Nuctalon
Chemical Information
Molecular Formula C16H11ClN4
CAS Registry Number 29975-16-4
SMILES C1C2=NN=CN2C3=C(C=C(C=C3)Cl)C(=N1)C4=CC=CC=C4
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Visual field defect17.17.01.001; 06.02.07.003--Not Available
Visual impairment06.02.06.008--Not Available
Vomiting07.01.07.003--
Weight decreased13.15.01.005--
Weight increased13.15.01.006--
Hypoacusis04.02.01.006--
Penile discharge21.12.01.005--Not Available
Musculoskeletal stiffness15.03.01.005--Not Available
Musculoskeletal discomfort15.03.04.001--Not Available
Affect lability19.04.01.001--Not Available
Vulvovaginal pruritus23.03.12.009; 21.08.02.004--Not Available
Paraesthesia oral07.05.03.003; 17.02.06.008--Not Available
Thyroid mass05.02.01.003--Not Available
Disturbance in sexual arousal19.08.04.003--Not Available
Malnutrition14.03.02.004--Not Available
Decreased appetite14.03.01.005; 08.01.09.028--
Ill-defined disorder08.01.03.049--Not Available
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