Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Estazolam
Drug ID BADD_D00819
Description A benzodiazepine with anticonvulsant, hypnotic, and muscle relaxant properties. It has been shown in some cases to be more potent than diazepam or nitrazepam.
Indications and Usage For the short-term management of insomnia characterized by difficulty in falling asleep, frequent nocturnal awakenings, and/or early morning awakenings.
Marketing Status Prescription; Discontinued
ATC Code N05CD04
DrugBank ID DB01215
KEGG ID D00311
MeSH ID D004949
PubChem ID 3261
TTD Drug ID D0P2CK
NDC Product Code 0591-0744; 51862-074; 12828-0077; 51862-069; 0591-0745; 70954-480; 70954-481; 51862-073; 51862-070; 48087-0031
Synonyms Estazolam | Tasedan | ProSom | D-40TA | D40TA | Nuctalon
Chemical Information
Molecular Formula C16H11ClN4
CAS Registry Number 29975-16-4
SMILES C1C2=NN=CN2C3=C(C=C(C=C3)Cl)C(=N1)C4=CC=CC=C4
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Paraesthesia17.02.06.005--
Pharyngitis11.01.13.003; 22.07.03.004; 07.05.07.004--
Photophobia17.17.02.006; 06.01.01.004--
Photosensitivity reaction23.03.09.003--
Pollakiuria20.02.02.007--
Pruritus23.03.12.001--
Purpura23.06.01.004; 01.01.04.003; 24.07.06.005--
Pyrexia08.05.02.003--
Rash23.03.13.001--Not Available
Rhinitis22.07.03.006; 11.01.13.004--
Seizure17.12.03.001--
Shock24.06.02.002--Not Available
Sinusitis11.01.13.005; 22.07.03.007--
Sleep disorder19.02.04.001--Not Available
Somnolence19.02.05.003; 17.02.04.006--
Stevens-Johnson syndrome23.03.01.007; 12.03.01.014; 11.07.01.005; 10.01.03.020--
Stupor19.02.05.004; 17.02.04.007--Not Available
Syncope24.06.02.012; 17.02.04.008; 02.01.02.008--
Tension19.06.02.005--Not Available
Thinking abnormal19.10.03.001; 17.02.05.023--Not Available
Thirst08.01.09.021; 14.03.02.007--Not Available
Thyroid neoplasm16.24.01.002; 05.02.05.002--Not Available
Tinnitus17.04.07.004; 04.04.01.002--
Tremor17.01.06.002--
Ulcer08.03.06.001--Not Available
Urinary hesitation20.02.02.009--Not Available
Urinary incontinence20.02.02.010; 17.05.01.008--
Urticaria23.04.02.001; 10.01.06.001--
Vaginal discharge21.08.02.002--
Vascular purpura24.07.06.011; 23.06.01.008; 01.01.04.007--Not Available
The 4th Page    First    Pre   4 5    Next   Last    Total 5 Pages