| Pharmaceutical Information |
| Drug Name |
Econazole nitrate |
| Drug ID |
BADD_D00741 |
| Description |
A broad spectrum antimycotic with some action against Gram positive bacteria. It is used topically in dermatomycoses also orally and parenterally. |
| Indications and Usage |
For topical application in the treatment of tinea pedis, tinea cruris, and tinea corporis caused by Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Microsporum canis, Microsporum audouini, Microsporum gypseum, and Epidermophyton floccosum, in the treatment of cutaneous candidiasis, and in the treatment of tinea versicolor. |
| Marketing Status |
Prescription |
| ATC Code |
D01AC03; G01AF05 |
| DrugBank ID |
DB01127
|
| KEGG ID |
D00881
|
| MeSH ID |
D004464
|
| PubChem ID |
68589
|
| TTD Drug ID |
D0EV8E
|
| NDC Product Code |
52565-022; 63629-8646; 63629-8647; 70512-029; 63629-8645; 55545-0452; 17337-0515; 49632-180; 23710-100; 51672-1303; 59088-752; 52935-0007; 68788-7406; 45802-466; 51927-0179; 63739-085; 51927-0040; 68788-8170; 49452-2699; 72275-735; 51552-1316 |
| Synonyms |
Econazole | Ekonazole | Gyno-Pervaryl 150 | Gyno Pervaryl 150 | Pevaryl | Econazole Nitrate | Nitrate, Econazole | Gyno-Pevaryl | Gyno Pevaryl | Gyno-Pevaril | Gyno Pevaril | GynoPevaril |
|
| Chemical Information |
| Molecular Formula |
C18H15Cl3N2O.HNO3 |
| CAS Registry Number |
24169-02-6 |
| SMILES |
C1=CC(=CC=C1COC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl)Cl.[N+](=O)(O)[O-] |
| Chemical Structure |
|
|
| ADR Related Proteins Induced by Drug |
| ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
| Not Available | Not Available | Not Available | Not Available | Not Available |
|
| ADRs Induced by Drug |
|
| ADR Term |
ADReCS ID |
ADR Frequency (FAERS)
|
ADR Severity Grade (FAERS)
|
ADR Severity Grade (CTCAE)
|
| Erythema | 23.03.06.001 | - | - | Not Available | | Pain | 08.01.08.004 | - | - | | | Pruritus | 23.03.12.001 | - | - | | | Rash pruritic | 23.03.12.002 | - | - | Not Available |
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