Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Echothiophate iodide
Drug ID BADD_D00739
Description A potent, long-acting irreversible cholinesterase inhibitor used as an ocular hypertensive in the treatment of glaucoma. Occasionally used for accomodative esotropia.
Indications and Usage For use in the treatment of subacute or chronic angle-closure glaucoma after iridectomy or where surgery is refused or contraindicated.
Marketing Status Prescription; Discontinued
ATC Code S01EB03
DrugBank ID DB01057
KEGG ID D02193
MeSH ID D004456
PubChem ID 10547
TTD Drug ID D0U8AT
NDC Product Code 0046-1065; 65392-1402
Synonyms Echothiophate Iodide | Iodide, Echothiophate | Ecothiopate Iodide | Iodide, Ecothiopate | Ecothiophate Iodide | Iodide, Ecothiophate | 2-((Diethoxyphosphinyl)thio)-N,N,N,-trimethylethanaminium iodide | Phospholine Iodide | Iodide, Phospholine
Chemical Information
Molecular Formula C9H23INO3PS
CAS Registry Number 513-10-0
SMILES CCOP(=O)(OCC)SCC[N+](C)(C)C.[I-]
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Blepharospasm17.17.02.001; 06.05.01.001--Not Available
Burning sensation08.01.09.029; 17.02.06.001--Not Available
Cyst16.02.02.002; 08.03.05.001--Not Available
Dacryostenosis congenital06.06.04.008; 03.01.04.001--Not Available
Erythema23.03.06.001--Not Available
Heart rate irregular13.14.04.003--Not Available
Intraocular pressure increased13.07.04.002--Not Available
Iris cyst16.34.01.001; 06.12.01.001--Not Available
Iritis10.02.01.022; 06.04.03.002--Not Available
Lacrimation increased06.08.02.004--
Lenticular opacities06.06.01.003--Not Available
Migraine24.03.05.003; 17.14.02.001--Not Available
Muscle twitching15.05.03.005--Not Available
Myopia06.02.04.002--Not Available
Pain08.01.08.004--
Retinal detachment12.01.04.004; 06.09.03.003--
Uveitis10.02.01.023; 06.04.03.003--
Vision blurred06.02.06.007; 17.17.01.010--
Conjunctival hyperaemia06.04.01.004--Not Available
Ciliary hyperaemia06.04.03.004--Not Available
Conjunctival disorder06.06.02.004--Not Available
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