Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Dulaglutide
Drug ID BADD_D00733
Description Dulaglutide, marketed by Eli Lilly as Trulicity, is a once-weekly subcutaneous glucagon-like peptide-1 (GLP-1) receptor agonist designed using recombinant DNA technology; it has been approved as an adjunct therapy to diet and exercise in the management of 2 diabetes (T2DM).[A236070] Dulaglutide was initially approved by the FDA in 2014, and in February 2020 was approved for use in patients with T2DM and multiple cardiovascular risk factors for the prevention of cardiovascular events. It is the first T2DM drug approved to reduce major adverse cardiovascular events (MACE) risk in primary and secondary prevention populations.[L34665]
Indications and Usage Indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
Marketing Status Prescription
ATC Code A10BJ05
DrugBank ID DB09045
KEGG ID D09889
MeSH ID C555680
PubChem ID Not Available
TTD Drug ID D03NAW
NDC Product Code 0002-1434; 62195-433; 54568-001; 0002-1402; 0002-2236; 0002-1433; 50090-5467; 62381-1434; 0002-1401; 62381-1433; 63419-0525; 0002-3182; 62195-434; 50090-3484; 50090-3483
Synonyms dulaglutide | LY 2189265 | LY-2189265 | LY2189265 | Trulicity
Chemical Information
Molecular Formula Not Available
CAS Registry Number 923950-08-7
SMILES Not Available
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Urticaria10.01.06.001; 23.04.02.001--
Vomiting07.01.07.003--
Vomiting projectile07.01.07.012--Not Available
Faecal volume increased07.01.03.009--Not Available
Electrocardiogram PR prolongation13.14.05.012--Not Available
Decreased appetite14.03.01.005; 08.01.09.028--
Immunology test13.06.03.007--Not Available
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