Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Dipyridamole
Drug ID BADD_D00692
Description A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
Indications and Usage For as an adjunct to coumarin anticoagulants in the prevention of postoperative thromboembolic complications of cardiac valve replacement and also used in prevention of angina.
Marketing Status Prescription; Discontinued
ATC Code B01AC07
DrugBank ID DB00975
KEGG ID D00302
MeSH ID D004176
PubChem ID 3108
TTD Drug ID D0F9GE
NDC Product Code 62559-236; 64980-133; 0115-1070; 62559-237; 69584-182; 65841-664; 64980-135; 65404-005; 65015-782; 65841-662; 51407-628; 0115-1071; 0527-1461; 51662-1447; 69584-183; 65841-663; 62559-235; 0641-2569; 0527-1463; 51407-626; 68166-003; 0404-9852; 66039-917; 0527-1462; 71205-894; 52584-569; 51927-1571; 51407-627; 70896-2025; 68382-187; 0115-1072; 68382-188; 68382-189; 12660-0084; 69584-181; 17511-122; 64980-134; 71205-896; 71205-895
Synonyms Dipyridamole | Dipyramidole | Apo-Dipyridamole | Apo Dipyridamole | Cerebrovase | Persantine | Persantin | Curantil | Curantyl | Kurantil | Miosen | Novo-Dipiradol | Novo Dipiradol | Antistenocardin | Cléridium
Chemical Information
Molecular Formula C24H40N8O4
CAS Registry Number 58-32-2
SMILES C1CCN(CC1)C2=NC(=NC3=C2N=C(N=C3N4CCCCC4)N(CCO)CCO)N(CCO)CCO
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Ischaemia24.04.02.004--Not Available
Mediastinal disorder22.09.03.001--Not Available
Perineal pain21.10.01.003--
Ill-defined disorder08.01.03.049--Not Available
Blood disorder01.05.01.004--Not Available
Cardiac fibrillation02.03.02.021--Not Available
Unevaluable event08.01.03.0510.006711%Not Available
Anorectal discomfort07.03.03.003--Not Available
Procedural haemorrhage24.07.01.053; 12.02.05.036--
Depersonalisation/derealisation disorder19.14.01.004--Not Available
Splenic injury12.01.02.015; 01.09.02.0160.006711%Not Available
Peritoneal haematoma07.07.02.006; 24.07.02.0540.008948%Not Available
Stress cardiomyopathy24.04.04.026; 02.04.01.0120.004474%Not Available
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