Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Diazoxide
Drug ID BADD_D00649
Description A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
Indications and Usage Used parentally to treat hypertensive emergencies. Also used to treat hypoglycemia secondary to insulinoma.
Marketing Status Prescription; Discontinued
ATC Code C02DA01; V03AH01
DrugBank ID DB01119
KEGG ID D00294
MeSH ID D003981
PubChem ID 3019
TTD Drug ID D07WEP
NDC Product Code 38779-0324; 0575-6200; 58159-039; 52952-003; 69575-4025; 62991-2857; 49452-2541; 51927-2742; 38779-3184; 71052-664; 0254-1010; 13517-100; 14501-0096; 45562-1740; 51552-1582
Synonyms Diazoxide | Proglycem | Hyperstat
Chemical Information
Molecular Formula C8H7ClN2O2S
CAS Registry Number 364-98-7
SMILES CC1=NS(=O)(=O)C2=C(N1)C=CC(=C2)Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Weight increased13.15.01.006--
Hypoacusis04.02.01.006--
Emotional distress19.04.02.008--Not Available
Subileus07.13.01.0040.000646%Not Available
Necrotising colitis07.08.01.0130.000969%Not Available
Haemorrhage24.07.01.002--Not Available
Pancreatic necrosis07.18.02.004--
Vasodilation procedure25.03.01.001--Not Available
Sudden hearing loss04.02.01.009--Not Available
Decreased appetite14.03.01.005; 08.01.09.028--
Ill-defined disorder08.01.03.049--Not Available
Pulmonary arterial hypertension22.06.01.002; 24.08.03.0030.000646%Not Available
Bone cyst16.11.03.001; 15.02.04.0260.000646%Not Available
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