Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Dexmedetomidine
Drug ID BADD_D00629
Description An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
Indications and Usage For sedation of initially intubated and mechanically ventilated patients during treatment in an intensive care setting, also used in pain relief; anxiety reduction and analgesia
Marketing Status Prescription
ATC Code N05CM18
DrugBank ID DB00633
KEGG ID D00514
MeSH ID D020927
PubChem ID 5311068
TTD Drug ID D0U3DU
NDC Product Code 55150-209; 66794-230; 70860-605; 62068-308; 71872-7150; 66794-238; 66794-233; 16729-432; 71288-505; 67457-251; 16729-239
Synonyms Dexmedetomidine | MPV-1440 | MPV 1440 | MPV1440 | Precedex | Dexmedetomidine Hydrochloride | Hydrochloride, Dexmedetomidine
Chemical Information
Molecular Formula C13H16N2
CAS Registry Number 113775-47-6
SMILES CC1=C(C(=CC=C1)C(C)C2=CN=CN2)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Neuritis17.09.03.001--Not Available
Neuroleptic malignant syndrome17.05.02.003; 15.05.04.015; 12.03.01.003; 08.05.01.0050.000236%Not Available
Neuropathy peripheral17.09.03.003--Not Available
Nodal rhythm02.03.02.0060.000903%Not Available
Oedema14.05.06.010; 08.01.07.0060.000602%Not Available
Oedema peripheral14.05.06.011; 08.01.07.007; 02.05.04.0070.000903%
Oliguria20.01.03.004--Not Available
Oxygen saturation decreased13.02.01.0040.002107%Not Available
Pain08.01.08.004--
Photopsia17.17.01.006; 06.02.06.004--
Platelet count decreased13.01.04.0010.001505%
Pleural effusion22.05.02.002--
Pneumonia22.07.01.003; 11.01.09.0030.002107%Not Available
Pneumonia aspiration22.01.01.0050.000628%Not Available
Pneumothorax22.05.02.003--
Polyneuropathy17.09.03.0120.000602%Not Available
Polyuria20.02.03.0020.001505%Not Available
Pregnancy18.08.02.004--Not Available
Prinzmetal angina24.04.04.015; 02.02.02.0190.001204%Not Available
Pulmonary congestion24.03.08.001; 22.01.03.002; 02.05.02.002--Not Available
Pulmonary oedema22.01.03.003; 02.05.02.003--
Pyrexia08.05.02.0030.010535%
Rash23.03.13.001--Not Available
Red blood cell count decreased13.01.05.0070.000903%Not Available
Respiratory acidosis22.02.02.004; 14.01.04.002--Not Available
Respiratory arrest22.02.01.0090.000393%Not Available
Respiratory depression22.02.01.010; 17.02.05.0470.002408%Not Available
Respiratory distress22.02.01.0120.000903%Not Available
Respiratory failure22.02.06.002; 14.01.04.0030.000236%
Respiratory rate decreased13.15.01.003--Not Available
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