Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Dexmedetomidine
Drug ID BADD_D00629
Description An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
Indications and Usage For sedation of initially intubated and mechanically ventilated patients during treatment in an intensive care setting, also used in pain relief; anxiety reduction and analgesia
Marketing Status Prescription
ATC Code N05CM18
DrugBank ID DB00633
KEGG ID D00514
MeSH ID D020927
PubChem ID 5311068
TTD Drug ID D0U3DU
NDC Product Code 55150-209; 66794-230; 70860-605; 62068-308; 71872-7150; 66794-238; 66794-233; 16729-432; 71288-505; 67457-251; 16729-239
Synonyms Dexmedetomidine | MPV-1440 | MPV 1440 | MPV1440 | Precedex | Dexmedetomidine Hydrochloride | Hydrochloride, Dexmedetomidine
Chemical Information
Molecular Formula C13H16N2
CAS Registry Number 113775-47-6
SMILES CC1=C(C(=CC=C1)C(C)C2=CN=CN2)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hyperthermia12.05.01.002; 08.05.01.0010.002709%Not Available
Hyperthermia malignant08.05.01.0020.000236%Not Available
Hyperventilation22.02.01.006; 19.01.02.0040.000602%Not Available
Hypoalbuminaemia14.10.01.002; 09.01.02.003--
Hypocalcaemia14.04.01.004--
Hypoglycaemia14.06.03.001; 05.06.03.001--
Hypokalaemia14.05.03.002--
Hypomagnesaemia14.04.02.001--
Hypophosphataemia14.04.03.001--
Hypopnoea22.02.01.0210.000903%Not Available
Hypotension24.06.03.0020.005719%
Hypothermia12.05.03.001; 08.05.01.003--
Hypoventilation22.02.01.007--Not Available
Hypovolaemia14.05.05.002--Not Available
Hypoxia22.02.02.0030.000903%
Illusion19.10.02.005--Not Available
Infection11.01.08.002--Not Available
Laceration23.03.11.004; 12.01.06.0060.003311%Not Available
Laryngeal pain22.02.05.036--
Laryngospasm22.04.02.0020.001505%
Leukocytosis01.02.01.002--
Light anaesthesia25.01.03.003--Not Available
Loss of consciousness17.02.04.0040.001505%Not Available
Malabsorption14.02.01.004; 07.17.01.0010.000602%
Metabolic acidosis14.01.01.003--Not Available
Myocardial infarction24.04.04.009; 02.02.02.007--
Myocardial ischaemia24.04.04.010; 02.02.02.0080.001806%Not Available
Nausea07.01.07.001--
Nephropathy20.05.03.001--Not Available
Neuralgia17.02.07.005--
The 4th Page    First    Pre   4 5 6 7    Next   Last    Total 7 Pages