Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Dexmedetomidine
Drug ID BADD_D00629
Description An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
Indications and Usage For sedation of initially intubated and mechanically ventilated patients during treatment in an intensive care setting, also used in pain relief; anxiety reduction and analgesia
Marketing Status Prescription
ATC Code N05CM18
DrugBank ID DB00633
KEGG ID D00514
MeSH ID D020927
PubChem ID 5311068
TTD Drug ID D0U3DU
NDC Product Code 55150-209; 66794-230; 70860-605; 62068-308; 71872-7150; 66794-238; 66794-233; 16729-432; 71288-505; 67457-251; 16729-239
Synonyms Dexmedetomidine | MPV-1440 | MPV 1440 | MPV1440 | Precedex | Dexmedetomidine Hydrochloride | Hydrochloride, Dexmedetomidine
Chemical Information
Molecular Formula C13H16N2
CAS Registry Number 113775-47-6
SMILES CC1=C(C(=CC=C1)C(C)C2=CN=CN2)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Bronchospasm22.03.01.004; 10.01.03.012--
Carbon dioxide increased13.02.01.011--Not Available
Cardiac arrest02.03.04.0010.001649%
Cardiac output decreased13.14.02.001--Not Available
Cardiac tamponade02.06.01.0010.000602%
Cardio-respiratory arrest22.02.06.007; 02.03.04.0020.000550%Not Available
Cardiovascular disorder24.03.02.009; 02.01.01.001--Not Available
Cerebrovascular accident24.03.05.001; 17.08.01.007--
Chills15.05.03.016; 08.01.09.001--
Circulatory collapse24.06.02.0010.001204%Not Available
Confusional state19.13.01.001; 17.02.03.005--
Constipation07.02.02.001--
Cough22.02.03.001--
Death08.04.01.001--
Decubitus ulcer23.03.11.006--Not Available
Delayed recovery from anaesthesia17.02.04.011; 12.02.12.0030.000602%Not Available
Delirium19.13.02.0010.000903%
Depressed level of consciousness17.02.04.0020.001204%
Dermatitis23.03.04.002--Not Available
Diabetes insipidus14.05.07.003; 05.03.03.0040.001505%Not Available
Diarrhoea07.02.01.001--
Diastolic hypertension24.08.02.006--Not Available
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Drug ineffective08.06.01.006--Not Available
Drug withdrawal convulsions17.12.03.016; 08.06.02.0030.006321%Not Available
Drug withdrawal syndrome19.07.02.011; 08.06.02.0040.000157%Not Available
Dry mouth07.06.01.002--
Dyspnoea22.02.01.004; 02.01.03.002--
Electrocardiogram QT prolonged13.14.05.0040.000602%
Electrocardiogram ST segment abnormal13.14.05.0170.000602%Not Available
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