Pharmaceutical Information |
Drug Name |
Dexchlorpheniramine |
Drug ID |
BADD_D00626 |
Description |
Dexchlorpheniramine is a potent S-enantiomer of chlorpheniramine. The salt form dexchlorpheniramine maleate as the active ingredient is available as a prescription drug indicated for adjunctive therapy for allergic and anaphylactic reactions. It is an antihistamine drug with anticholinergic (drying) and sedative actions. It disrupts histamine signaling by competing with histamine for cell receptor sites on effector cells. |
Indications and Usage |
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Marketing Status |
Prescription; Discontinued |
ATC Code |
R06AB02 |
DrugBank ID |
DB13679
|
KEGG ID |
D07803
|
MeSH ID |
C018904
|
PubChem ID |
33036
|
TTD Drug ID |
D05ZGQ
|
NDC Product Code |
Not Available |
Synonyms |
dexchlorpheniramine | dexclorfeniramine | dexchlorpheniramine, (+-)-isomer | dexchlorpheniramine, (R)-isomer | dexchlorpheniramine, monohydrochloride, (S)-isomer | Dexclor | Polaramine | Polaramin | dexchlorpheniramine monohydrochloride | Polaronil | dexchlorpheniramine maleate | dextrochlorpheniramine maleate | dexchlorpheniramine maleate (1:1), (+-)-isomer | dexchlorpheniramine maleate (1:1), (R)-isomer | dexchlorpheniramine maleate (1:1), (S)-isomer | dexchlorpheniramine sodium maleate (1:1) | Polargen TD |
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Chemical Information |
Molecular Formula |
C16H19ClN2 |
CAS Registry Number |
25523-97-1 |
SMILES |
CN(C)CCC(C1=CC=C(C=C1)Cl)C2=CC=CC=N2 |
Chemical Structure |
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ADR Related Proteins Induced by Drug |
ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
Not Available | Not Available | Not Available | Not Available | Not Available |
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ADRs Induced by Drug |
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