Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Delavirdine mesylate
Drug ID BADD_D00604
Description A potent, non-nucleoside reverse transcriptase inhibitor with activity specific for HIV-1.
Indications and Usage For the treatment of HIV-1 infection in combination with appropriate antiretroviral agents when therapy is warranted
Marketing Status Prescription
ATC Code J05AG02
DrugBank ID DB00705
KEGG ID D00895
MeSH ID D020008
PubChem ID 441386
TTD Drug ID D0G6SD
NDC Product Code Not Available
Synonyms Delavirdine | Rescriptor | U-90152 | U 90152 | U90152 | U-90152S | U 90152S | U90152S | Delavirdine Mesylate | Mesylate, Delavirdine
Chemical Information
Molecular Formula C23H32N6O6S2
CAS Registry Number 147221-93-0
SMILES CC(C)NC1=C(N=CC=C1)N2CCN(CC2)C(=O)C3=CC4=C(N3)C=CC(=C4)NS(=O)(=O)C.CS(=O)(=O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Pruritus23.03.12.001--
Purpura24.07.06.005; 23.06.01.004; 01.01.04.003--
Pyrexia08.05.02.003--
Rash23.03.13.001--Not Available
Renal pain20.02.03.003--Not Available
Restlessness19.11.02.002; 17.02.05.021--
Retching07.01.07.002--Not Available
Rhabdomyolysis15.05.05.002--
Rhinitis22.07.03.006; 11.01.13.004--
Salivary hypersecretion07.06.01.009--Not Available
Seborrhoea23.02.07.001--Not Available
Sialoadenitis11.01.04.002; 07.06.04.002--
Sinusitis22.07.03.007; 11.01.13.005--
Skin discolouration23.03.03.005--Not Available
Skin disorder23.03.03.007--Not Available
Skin exfoliation23.03.07.003--Not Available
Skin hypertrophy23.01.04.002--Not Available
Skin papilloma23.10.01.002; 16.26.01.002; 11.05.07.001--
Sleep disorder19.02.04.001--Not Available
Somnolence17.02.04.006; 19.02.05.003--
Spleen disorder01.09.02.003--Not Available
Stevens-Johnson syndrome23.03.01.007; 12.03.01.014; 11.07.01.005; 10.01.03.020--
Stomatitis07.05.06.005--
Tendon disorder15.07.01.002--Not Available
Tenosynovitis15.07.01.004--Not Available
Testicular pain21.13.01.005--
Tetany15.05.03.013; 14.04.01.005; 05.04.02.003--Not Available
Thirst14.03.02.007; 08.01.09.021--Not Available
Thrombocytopenia01.08.01.002--Not Available
Tinnitus17.04.07.004; 04.04.01.002--
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