Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Dalfampridine
Drug ID BADD_D00574
Description Dalfampridine is a potassium channel blocker used to help multiple sclerosis patients walk. This is the first drug that was specifically approved to help with mobility in these patients. FDA approved on January 22, 2010.
Indications and Usage Dalfampridine is a neurofunctional modifier that helps improve walking speed in patients with multiple sclerosis (MS).
Marketing Status Prescription
ATC Code N07XX07
DrugBank ID DB06637
KEGG ID D04127
MeSH ID D015761
PubChem ID 1727
TTD Drug ID D08YIN
NDC Product Code 38779-3205; 42571-338; 63190-0510; 46016-5042; 16729-292; 56125-427; 62756-429; 0054-0479; 42571-275; 51927-5030; 12817-054; 54382-125; 62756-038; 63190-0530; 51407-246; 65862-917; 65372-1157; 65862-863; 62991-3143; 67877-444; 10144-427; 0378-0509
Synonyms 4-Aminopyridine | 4 Aminopyridine | Dalfampridine | Pymadine | VMI-103 | VMI 103 | VMI103 | 4-Aminopyridine Sustained Release | 4 Aminopyridine Sustained Release | Sustained Release, 4-Aminopyridine | Fampridine-SR | Fampridine SR
Chemical Information
Molecular Formula C5H6N2
CAS Registry Number 504-24-5
SMILES C1=CN=CC=C1N
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
B-lymphocyte count13.01.06.0500.009150%Not Available
Light chain analysis increased13.06.05.0120.002614%Not Available
Foot deformity15.10.03.0050.003921%Not Available
Klebsiella infection11.02.03.0030.005229%Not Available
Neutrophil count abnormal13.01.06.0180.002614%Not Available
Culture positive13.08.02.0030.002614%Not Available
Proteus infection11.02.30.0010.002614%Not Available
Vitamin D increased13.02.05.0140.005229%Not Available
Vitamin B12 abnormal13.02.05.0120.005229%Not Available
Urinary tract infection pseudomonal11.02.12.007; 20.08.02.0130.007843%Not Available
Human papilloma virus test positive13.08.03.0270.002614%Not Available
JC virus test positive13.08.03.0300.010457%Not Available
Enterococcus test positive13.08.01.0080.005229%Not Available
Staphylococcus test positive13.08.01.0150.002614%Not Available
Streptococcus test positive13.08.01.0160.003921%Not Available
Escherichia test positive13.08.01.0090.014379%Not Available
Klebsiella test positive13.08.01.0110.006536%Not Available
Proteus test positive13.08.01.0120.003921%Not Available
Pseudomonas test positive13.08.01.0130.005229%Not Available
Pubis fracture15.08.06.004; 12.04.06.0040.005229%Not Available
Walking distance test abnormal13.15.01.0480.002614%Not Available
Eye contusion24.07.06.022; 12.01.04.024; 06.11.01.0110.002614%Not Available
Abdominal lymphadenopathy01.09.01.020; 07.11.01.0180.002614%Not Available
Uterine scar21.07.01.020; 12.02.14.0080.002614%Not Available
Lacunar stroke24.04.06.037; 17.08.01.0540.002614%Not Available
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