Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Dabigatran
Drug ID BADD_D00563
Description Dabigatran is the active form of the orally bioavailable prodrug [dabigatran etexilate].
Indications and Usage Not Available
Marketing Status approved; investigational
ATC Code B01AE07
DrugBank ID DB14726
KEGG ID D09707
MeSH ID D000069604
PubChem ID 216210
TTD Drug ID D0M7JT
NDC Product Code 51869-0030
UNII I0VM4M70GC
Synonyms Dabigatran | N-((2-(((4-(aminoiminomethyl)phenyl)amino)methyl)-1-methyl-1H-benzimidazol-5-yl)carbonyl)-N-2-pyridinyl-beta-alanine | BIBR 1048 | Pradaxa | Dabigatran Etexilate | Etexilate, Dabigatran | Dabigatran Etexilate Mesylate | Etexilate Mesylate, Dabigatran | Mesylate, Dabigatran Etexilate
Chemical Information
Molecular Formula C25H25N7O3
CAS Registry Number 211914-51-1
SMILES CN1C2=C(C=C(C=C2)C(=O)N(CCC(=O)O)C3=CC=CC=N3)N=C1CNC4=CC=C(C=C4)C(=N)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Medical device site haemorrhage24.07.01.101; 12.02.21.013; 08.07.01.0290.000245%Not Available
Mesenteric haemorrhage24.07.02.066; 07.12.03.0120.000245%Not Available
Myocardial injury02.04.02.0460.000245%Not Available
Normocytic anaemia01.03.02.0220.000489%Not Available
Pancreatolithiasis07.18.02.0160.000245%Not Available
Postictal paralysis17.01.04.0250.000245%Not Available
Prosthetic cardiac valve thrombosis27.01.01.004; 24.01.05.015; 08.07.07.003; 02.07.02.0140.000245%Not Available
Renal vein embolism24.01.11.006; 20.01.07.0220.000245%Not Available
Right hemisphere deficit syndrome19.21.01.016; 17.02.03.0240.000367%Not Available
Stroke in evolution24.03.05.021; 17.08.01.0780.000245%Not Available
Subcapsular renal haematoma20.01.02.021; 12.01.05.008; 24.07.07.0060.000612%Not Available
Subgaleal haematoma24.07.01.106; 18.04.19.001; 12.01.09.0240.000245%Not Available
Superficial vein thrombosis24.01.02.0160.001346%Not Available
Therapeutic product effect prolonged08.06.01.0540.000489%Not Available
Thrombophlebitis migrans16.32.01.016; 24.01.01.0430.000245%Not Available
Vertebrobasilar artery dissection24.02.04.008; 17.08.06.0060.000245%Not Available
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