Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Dabigatran
Drug ID BADD_D00563
Description Dabigatran is the active form of the orally bioavailable prodrug [dabigatran etexilate].
Indications and Usage Not Available
Marketing Status approved; investigational
ATC Code B01AE07
DrugBank ID DB14726
KEGG ID D09707
MeSH ID D000069604
PubChem ID 216210
TTD Drug ID D0M7JT
NDC Product Code 51869-0030
UNII I0VM4M70GC
Synonyms Dabigatran | N-((2-(((4-(aminoiminomethyl)phenyl)amino)methyl)-1-methyl-1H-benzimidazol-5-yl)carbonyl)-N-2-pyridinyl-beta-alanine | BIBR 1048 | Pradaxa | Dabigatran Etexilate | Etexilate, Dabigatran | Dabigatran Etexilate Mesylate | Etexilate Mesylate, Dabigatran | Mesylate, Dabigatran Etexilate
Chemical Information
Molecular Formula C25H25N7O3
CAS Registry Number 211914-51-1
SMILES CN1C2=C(C=C(C=C2)C(=O)N(CCC(=O)O)C3=CC=CC=N3)N=C1CNC4=CC=C(C=C4)C(=N)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Aphasia19.21.01.001; 17.02.03.0010.016074%
Apraxia19.21.01.002; 17.02.03.0020.000856%Not Available
Arterial thrombosis24.01.01.0020.002569%Not Available
Arteriosclerosis coronary artery24.04.04.012; 02.02.01.0110.000367%Not Available
Arteriovenous fistula24.03.03.0010.000245%Not Available
Atrial fibrillation02.03.03.0020.018251%
Atrial flutter02.03.03.0030.002569%
Atrial tachycardia02.03.03.0040.000245%
Atrioventricular block complete02.03.01.0030.001468%
Barrett's oesophagus07.11.03.0020.000245%Not Available
Benign prostatic hyperplasia21.04.02.0010.000367%Not Available
Bile duct stone09.02.02.0030.000856%Not Available
Bladder diverticulum20.03.01.0090.000783%Not Available
Bladder neoplasm20.03.04.002; 16.08.03.0020.000367%Not Available
Blindness transient17.17.01.004; 06.02.10.0060.000905%Not Available
Blindness unilateral06.02.10.007; 17.17.01.0160.001639%Not Available
Brain compression17.07.02.0050.000489%Not Available
Brain stem haemorrhage24.07.04.015; 17.08.01.0310.000489%Not Available
Brain stem infarction17.08.01.024; 24.04.06.0140.000489%Not Available
Calculus bladder20.04.03.0010.000245%Not Available
Cardiac arrest02.03.04.0010.012844%
Cardiac failure02.05.01.0010.025200%
Cardiac failure acute02.05.01.0050.001346%Not Available
Cardiac failure congestive02.05.01.0020.008196%Not Available
Cardiac tamponade02.06.01.0010.025934%
Cardiogenic shock24.06.02.006; 02.05.01.0030.004893%Not Available
Carotid artery stenosis24.04.06.001; 17.08.02.0010.002006%Not Available
Carotid artery thrombosis24.01.04.007; 17.08.01.0250.000734%Not Available
Cerebellar infarction24.04.06.007; 17.08.01.0130.001468%Not Available
Cerebral artery embolism24.01.04.001; 17.08.01.0010.004330%Not Available
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