Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Dabigatran
Drug ID BADD_D00563
Description Dabigatran is the active form of the orally bioavailable prodrug [dabigatran etexilate].
Indications and Usage Not Available
Marketing Status approved; investigational
ATC Code B01AE07
DrugBank ID DB14726
KEGG ID D09707
MeSH ID D000069604
PubChem ID 216210
TTD Drug ID D0M7JT
NDC Product Code 51869-0030
UNII I0VM4M70GC
Synonyms Dabigatran | N-((2-(((4-(aminoiminomethyl)phenyl)amino)methyl)-1-methyl-1H-benzimidazol-5-yl)carbonyl)-N-2-pyridinyl-beta-alanine | BIBR 1048 | Pradaxa | Dabigatran Etexilate | Etexilate, Dabigatran | Dabigatran Etexilate Mesylate | Etexilate Mesylate, Dabigatran | Mesylate, Dabigatran Etexilate
Chemical Information
Molecular Formula C25H25N7O3
CAS Registry Number 211914-51-1
SMILES CN1C2=C(C=C(C=C2)C(=O)N(CCC(=O)O)C3=CC=CC=N3)N=C1CNC4=CC=C(C=C4)C(=N)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Perforation08.01.03.0580.000367%Not Available
Stenosis08.01.03.0600.000245%Not Available
Multiple organ dysfunction syndrome08.01.03.0570.011866%
Device related thrombosis24.01.01.027; 08.07.05.0010.000856%Not Available
Adenocarcinoma of colon16.13.01.010; 07.21.01.0080.000367%Not Available
Antiphospholipid syndrome01.01.02.016; 24.01.01.029; 18.02.04.002; 10.04.01.0090.000979%Not Available
Arterial rupture24.03.02.027; 12.01.11.0100.000489%Not Available
Bladder cancer recurrent20.03.04.005; 16.08.01.0030.000367%Not Available
Bladder obstruction20.03.01.0120.000367%Not Available
Bleeding varicose vein24.10.04.0020.001076%Not Available
Brain neoplasm malignant17.20.04.002; 16.30.04.0020.000367%Not Available
Bronchial carcinoma22.08.01.015; 16.19.02.0040.000367%Not Available
Cardiac failure chronic02.05.01.0090.000856%Not Available
Cerebellar haemorrhage17.08.01.046; 24.07.04.0230.001957%Not Available
Cerebral artery thrombosis24.01.04.008; 17.08.01.0260.000979%Not Available
Cholangitis acute09.02.01.0060.000612%Not Available
Coronary artery embolism24.01.05.007; 02.02.01.0130.000489%Not Available
Diverticulum intestinal haemorrhagic24.07.02.043; 07.10.01.0030.002080%Not Available
Exsanguination24.07.01.0660.000612%Not Available
Extravasation blood24.07.01.0670.000367%Not Available
Gastrointestinal angiodysplasia24.03.03.007; 07.15.04.0010.000489%Not Available
Haemorrhagic cerebral infarction24.07.04.026; 17.08.01.0500.000979%Not Available
Haemorrhagic infarction24.04.02.0080.001101%Not Available
Hemianopia homonymous17.17.01.024; 06.02.07.0070.000856%Not Available
Hepatic haematoma24.07.01.071; 09.01.06.016; 12.01.17.0080.000489%Not Available
Hilar lymphadenopathy22.09.03.005; 01.09.01.0230.000245%Not Available
Incarcerated hernia08.01.04.0040.001713%Not Available
Intracranial tumour haemorrhage16.32.03.023; 24.07.04.028; 17.08.01.0520.000245%Not Available
Jugular vein thrombosis24.01.02.0070.000367%Not Available
Lung carcinoma cell type unspecified stage IV22.08.01.019; 16.19.02.0060.000245%Not Available
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