Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Cyproterone acetate
Drug ID BADD_D00555
Description An anti-androgen that, in the form of its acetate (cyproterone acetate), also has progestational properties. It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, in combination with estrogen, for the therapy of severe acne and hirsutism in females.
Indications and Usage For the palliative treatment of patients with advanced prostatic carcinoma.
Marketing Status Not Available
ATC Code G03HA01
DrugBank ID DB04839
KEGG ID D01368
MeSH ID D017373
PubChem ID 9880
TTD Drug ID Not Available
NDC Product Code 59010-000; 46439-8720; 53104-7635
Synonyms Cyproterone Acetate | Cyproterone Acetate, (17 alpha)-Isomer | Cyproterone Acetate, (1 alpha,2 alpha,9 beta,10 alpha)-Isomer | Androcur | Cyproterone Acetate, (1 alpha,2 alpha)-Isomer
Chemical Information
Molecular Formula C24H29ClO4
CAS Registry Number 427-51-0
SMILES CC(=O)C1(CCC2C1(CCC3C2C=C(C4=CC(=O)C5CC5C34C)Cl)C)OC(=O)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Embolism24.01.01.009--
Intra-abdominal haemorrhage07.12.02.008; 24.07.02.035--
Malnutrition14.03.02.004--Not Available
Mediastinal disorder22.09.03.001--Not Available
Mental disorder19.07.01.002--Not Available
Decreased appetite14.03.01.005; 08.01.09.028--
Erectile dysfunction19.08.04.001; 21.03.01.007--
Ill-defined disorder08.01.03.049--Not Available
Polyp16.02.02.005; 08.01.06.010--Not Available
Blood disorder01.05.01.004--Not Available
Hepatobiliary disease09.01.08.003--Not Available
Urine analysis abnormal13.13.02.008--Not Available
Foetal chromosome abnormality03.12.02.004; 18.03.02.009--Not Available
Hepatic cancer16.07.02.004; 09.04.02.008--Not Available
Hepatocellular carcinoma16.07.02.005; 09.04.02.010--Not Available
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