Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Cromolyn sodium
Drug ID BADD_D00539
Description A chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells. It is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect an established asthmatic attack.
Indications and Usage For the management of patients with bronchial asthma. Also used in the treatment of vernal keratoconjunctivitis, vernal conjunctivitis, and vernal keratitis.
Marketing Status Prescription; OTC; Discontinued
ATC Code A07EB01; D11AH03; R01AC01; R03BC01; S01GX01
DrugBank ID DB01003
KEGG ID D00526
MeSH ID D004205
PubChem ID 27503
TTD Drug ID D0G7IY
NDC Product Code 53002-0140; 71205-230; 42571-132; 76003-0773; 61314-237; 0037-0678; 71052-686; 71205-085; 0172-6406; 57782-397; 82298-910; 52183-199; 17478-291; 73377-119; 12780-4960; 50090-3042; 63629-2485; 62255-1321; 63629-2483; 38779-0301; 62991-1038; 12828-0062; 51525-0470; 51552-0423; 69784-200; 17337-0511; 49452-0006; 50090-1202; 16571-600; 66219-0531; 51927-5178
Synonyms Cromolyn Sodium | Sodium Cromoglycate | Cromoglycate, Sodium | Disodium Cromoglycate | Cromoglycate, Disodium | Aarane | Bicromat Spray | Cromoglycate | Opticrom | FPL-670 | FPL 670 | FPL670 | Intal | Lomudal | Nalcrom | Nasalcrom | Vicrom | Cromolyn | Cromoglicic Acid | Acid, Cromoglicic | Cromoglycic Acid | Acid, Cromoglycic
Chemical Information
Molecular Formula C23H14Na2O11
CAS Registry Number 15826-37-6
SMILES C1=CC2=C(C(=C1)OCC(COC3=CC=CC4=C3C(=O)C=C(O4)C(=O)[O-])O)C(=O)C=C(O2)C(=O)[O-].[ Na+].[Na+]
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Dry eye06.08.02.001--
Dyspnoea22.02.01.004; 02.01.03.002--
Eye irritation06.04.05.003--Not Available
Eye pain06.08.03.002--
Hordeolum11.01.06.002; 06.04.04.006--Not Available
Instillation site pain12.07.01.008; 08.02.01.008--Not Available
Lacrimation increased06.08.02.004--
Oedema08.01.07.006; 14.05.06.010--Not Available
Rash23.03.13.001--Not Available
Type I hypersensitivity10.01.03.006--Not Available
Conjunctival hyperaemia06.04.01.004--Not Available
Eye oedema06.08.03.013--Not Available
Eye pruritus06.04.05.006--Not Available
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