| Pharmaceutical Information |
| Drug Name |
Crofelemer |
| Drug ID |
BADD_D00536 |
| Description |
Crofelemer, previously known as the investigational drug SP-303, is a novel proanthocyanidin purified from the bark latex of the Amazonian Croton tree Croton lechleri. It is marketed under the brand name Fulyzaq and indicated for the symptomatic treatment of non-infectious diarrhea in adult patients with HIV/AIDS who are taking antiretroviral therapy. |
| Indications and Usage |
For the symptomatic treatment of non-infectious diarrhea in adult patients with HIV/AIDS who are taking antiretroviral therapy. |
| Marketing Status |
Prescription |
| ATC Code |
A07XA06 |
| DrugBank ID |
DB04941
|
| KEGG ID |
D03605
|
| MeSH ID |
C546704
|
| PubChem ID |
36511
|
| TTD Drug ID |
D09VXM
|
| NDC Product Code |
70564-802; 66039-854 |
| Synonyms |
crofelemer | Fulyzaq |
|
| Chemical Information |
| Molecular Formula |
C63H98N18O13S |
| CAS Registry Number |
33507-63-0 |
| SMILES |
CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)CNC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC2=CC=CC=C2)NC(
=O)C(CCC(=O)N)NC(=O)C(CCC(=O)N)NC(=O)C3CCCN3C(=O)C(CCCCN)NC(=O)C4CCCN4C(=O)C(CCC
N=C(N)N)N |
| Chemical Structure |
|
|
| ADR Related Proteins Induced by Drug |
| ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
| Not Available | Not Available | Not Available | Not Available | Not Available |
|
| ADRs Induced by Drug |
|
|
