| Pharmaceutical Information |
| Drug Name |
Corticotropin |
| Drug ID |
BADD_D00531 |
| Description |
Corticotropin (ACTH or adrenocorticotropic hormone) is a polypeptide hormone produced and secreted by the pituitary gland. It is an important player in the hypothalamic-pituitary-adrenal axis. |
| Indications and Usage |
For use as a diagnostic agent in the screening of patients presumed to have adrenocortical insufficiency.
Purified corticotropin for injection is indicated for a variety of allergic and autoimmune conditions.[L39150] |
| Marketing Status |
approved; investigational; vet_approved |
| ATC Code |
H01AA01 |
| DrugBank ID |
DB01285
|
| KEGG ID |
D00146
|
| MeSH ID |
D000324
|
| PubChem ID |
16132265
|
| TTD Drug ID |
D0R4HQ
|
| NDC Product Code |
51552-1613; 59149-005; 61200-004; 38779-1904; 63474-200 |
| UNII |
K0U68Q2TXA
|
| Synonyms |
Adrenocorticotropic Hormone | Hormone, Adrenocorticotropic | ACTH (1-39) | ACTH | Corticotrophin | Corticotropin | Corticotropin (1-39) | Corticotrophin (1-39) | Adrenocorticotrophic Hormone | Hormone, Adrenocorticotrophic | 1-39 ACTH | Adrenocorticotropin |
|
| Chemical Information |
| Molecular Formula |
C207H308N56O58S |
| CAS Registry Number |
9002-60-2 |
| SMILES |
CC(C)CC(C(=O)NC(CCC(=O)O)C(=O)NC(CC1=CC=CC=C1)C(=O)O)NC(=O)C2CCCN2C(=O)C(CC3=CC=
CC=C3)NC(=O)C(C)NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C(CO)NC(=O)C(CCC(=O)O)NC(=O)C(C
C(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)CNC(=O)C(CC(=O)N)NC(=O)C4CCCN4C(=O)C(CC5
=CC=C(C=C5)O)NC(=O)C(C(C)C)NC(=O)C(CCCCN)NC(=O)C(C(C)C)NC(=O)C6CCCN6C(=O)C(CCCNC
(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)CNC(=O)C(C(C)C)NC(=O)
C7CCCN7C(=O)C(CCCCN)NC(=O)CNC(=O)C(CC8=CNC9=CC=CC=C98)NC(=O)C(CCCNC(=N)N)NC(=O)C
(CC1=CC=CC=C1)NC(=O)C(CC1=CN=CN1)NC(=O)C(CCC(=O)O)NC(=O)C(CCSC)NC(=O)C(CO)NC(=O)
C(CC1=CC=C(C=C1)O)NC(=O)C(CO)N |
| Chemical Structure |
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| ADRs Induced by Drug |
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