| Drug Name |
Collagenase clostridium histolyticum |
| Drug ID |
BADD_D00525 |
| Description |
Collagenase clostridium histolyticum is an enzyme produced by the bacterium Clostridium histolyticum. It is beneficial in the breakdown of collagen plaques for the treatment of Dupuytren's contracture and Peyronie's disease.[L14882] The topical formulation is used for the debridement of necrotic tissue due to burns or chronic ulcers.[L14912]
On July 6, 2020 a combination of injectable bacterial collagenases was approved by the FDA for the treatment of cellulite in adult women.[L14872] Also known as Qwo, this injection is the first approved injectable treatment for cellulite and was developed by Endo International.[L14892] |
| Indications and Usage |
Used to promote debridement of necrotic tissue in the treatment of severe burns and dermal ulcers including decubitus ulcers. |
| Marketing Status |
Prescription |
| ATC Code |
M09AB02 |
| DrugBank ID |
DB00048
|
| KEGG ID |
D09596
|
| MeSH ID |
D003012
|
| PubChem ID |
Not Available
|
| TTD Drug ID |
D0I4ZQ
|
| NDC Product Code |
73611-300; 65044-7466; 66887-003 |
| Synonyms |
Microbial Collagenase | Clostridium histolyticum Collagenase | Collagenase, Clostridium histolyticum | Nucleolysin | Collagenase, Microbial | Collalysine | Clostridiopeptidase A | Collagenase Clostridium histolyticum | Clostridium histolyticum, Collagenase | histolyticum, Collagenase Clostridium | Collagenase-Like Peptidase | Collagenase Like Peptidase | Peptidase, Collagenase-Like |
