Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Clopidogrel
Drug ID BADD_D00504
Description Clopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and stroke.[A180508,L7213] Clopidogrel is indicated to reduce the risk of myocardial infarction for patients with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and in recent MI, stroke, or established peripheral arterial disease,[L7213] It has been shown to be superior to [aspirin] in reducing cardiovascular outcomes in patients with cardiovascular disease and provides additional benefit to patients with acute coronary syndromes already taking aspirin.[A180547] Clopidogrel was granted FDA approval on 17 November 1997.[L7213]
Indications and Usage Clopidogrel is indicated to reduce the risk of myocardial infarction for patients with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and in recent MI, stroke, or established peripheral arterial disease,[L7213]
Marketing Status approved
ATC Code B01AC04
DrugBank ID DB00758
KEGG ID D07729; D10823; D10824
MeSH ID D000077144
PubChem ID 60606
TTD Drug ID D0N0TZ
NDC Product Code 42543-714; 50090-4918; 52605-083; 16729-218; 0024-1171; 68788-8190; 72578-012; 65977-0037; 52605-082; 63187-362; 63629-4728; 70518-0400; 33342-060; 42543-713; 65162-414; 0093-7314; 16729-219; 61919-007; 67296-1840; 50090-2598; 50090-5781; 0024-1332; 61919-737; 70771-1062; 16714-052; 68071-2813; 68071-4138; 71335-0581
UNII A74586SNO7
Synonyms Clopidogrel | SC 25989C | SC 25990C | SR 25989 | Clopidogrel-Mepha | Clopidogrel Mepha | Clopidogrel Sandoz | Iscover | Clopidogrel Napadisilate | Clopidogrel Hydrochloride | PCR 4099 | PCR-4099 | Clopidogrel Besylate | Clopidogrel Besilate | Clopidogrel, (+)(S)-isomer | Plavix | Clopidogrel Bisulfate
Chemical Information
Molecular Formula C16H16ClNO2S
CAS Registry Number 113665-84-2
SMILES COC(=O)C(C1=CC=CC=C1Cl)N2CCC3=C(C2)C=CS3
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Haemobilia24.07.01.049; 09.01.08.0090.000064%Not Available
Intestinal haemorrhage24.07.02.031; 07.12.03.0050.000043%Not Available
Early satiety07.01.06.027; 14.03.01.010; 08.01.09.0040.000032%Not Available
Angiopathy24.03.02.0070.000021%Not Available
Epidermal necrosis23.03.03.0350.000021%Not Available
Extremity necrosis24.04.03.0120.000032%Not Available
Drug resistance08.06.01.0050.000396%Not Available
Hepatic enzyme increased13.03.04.028--Not Available
Ischaemic cerebral infarction24.04.06.013; 17.08.01.0220.000086%Not Available
Aortic rupture24.03.04.009; 12.01.11.0070.000021%Not Available
Appetite disorder19.09.01.002; 14.03.01.0040.000021%Not Available
Cardiac disorder02.11.01.003--Not Available
Eye movement disorder17.02.05.025; 06.05.02.0080.000043%Not Available
Embolism24.01.01.0090.000086%
Infarction24.04.02.0170.000043%Not Available
Intra-abdominal haemorrhage12.01.17.011; 24.07.02.035; 07.12.02.0080.000021%
Ischaemia24.04.02.0040.000075%Not Available
Ischaemic stroke24.04.06.010; 17.08.01.0180.001070%Not Available
Malnutrition14.03.02.0040.000043%Not Available
Mediastinal disorder22.09.03.001--Not Available
Mental disorder19.07.01.002--Not Available
Motor dysfunction17.01.02.031; 15.05.06.0060.000075%Not Available
Mucosal haemorrhage24.07.01.011; 08.01.06.0050.000021%Not Available
Erectile dysfunction21.03.01.007; 19.08.04.0010.000096%
Psychiatric symptom19.01.02.0010.000032%Not Available
Inner ear disorder04.04.02.002--Not Available
Red blood cell abnormality01.07.02.006--Not Available
Ulcer haemorrhage08.03.06.003; 24.07.01.0400.000096%Not Available
Blood disorder01.05.01.0040.000058%Not Available
Cardiac fibrillation02.03.02.0210.000021%Not Available
The 21th Page    First    Pre   21 22 23 24 25    Next   Last    Total 27 Pages
ADReCS-Target
Drug Name ADR Term Target
Tip:  Drug Name  ADR Term  Protein  Variation  Gene