Drug Name |
Clonidine |
Drug ID |
BADD_D00502 |
Description |
Clonidine is an imidazole derivate that acts as an agonist of alpha-2 adrenoceptors.[A180559] This activity is useful for the treatment of hypertension, severe pain, and ADHD.[L7237,L7240,L7243,L7246]
Clonidine was granted FDA approval on 3 September 1974.[L7237] |
Indications and Usage |
May be used as an adjunct in the treatment of hypertension, as an epidural infusion as an adjunct treatment in the management of severe cancer pain that is not relieved by opiate analgesics alone, for differential diagnosis of pheochromocytoma in hypertensive patients, prophylaxis of vascular migraine headaches, treatment of severe dysmenorrhea, management of vasomotor symptoms associated with menopause, rapid detoxification in the management of opiate withdrawal, treatment of alcohol withdrawal used in conjunction with benzodiazepines, management of nicotine dependence, topical use to reduce intraocular pressure in the treatment of open-angle and secondary glaucoma and hemorrhagic glaucoma associated with hypertension, and in the treatment of attention-deficit hyperactivity disorder (ADHD). |
Marketing Status |
Prescription; Discontinued |
ATC Code |
C02AC01; N02CX02; S01EA04 |
DrugBank ID |
DB00575
|
KEGG ID |
D00281
|
MeSH ID |
D003000
|
PubChem ID |
2803
|
TTD Drug ID |
D03SKR
|
NDC Product Code |
69988-0033; 0597-0033; 51862-453; 50742-247; 51862-455; 0591-3508; 0591-3509; 0597-0032; 0378-0872; 0597-0031; 82089-102; 0378-0873; 0378-0871; 51862-454; 82089-103; 46708-830; 82089-101; 71511-503; 39822-2010; 39822-2000; 0591-3510; 69238-1426 |
Synonyms |
Clonidine | Klofenil | Clofenil | Chlophazolin | Clonidine Dihydrochloride | Dihydrochloride, Clonidine | Clonidine Hydrochloride | Hydrochloride, Clonidine | Clonidine Monohydrochloride | Monohydrochloride, Clonidine | Clonidine Monohydrobromide | Monohydrobromide, Clonidine | ST-155 | ST 155 | ST155 | Gemiton | Hemiton | Isoglaucon | Klofelin | Clofelin | Clopheline | M-5041T | M 5041T | M5041T | Catapres | Catapresan | Catapressan | Dixarit |