Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Clobetasol
Drug ID BADD_D00489
Description Clobetasol is under investigation for the treatment of Scleroderma. Clobetasol has been investigated for the prevention of Psoriasis and Cutaneous Atrophy Due to Corticosteroids.
Indications and Usage
Marketing Status Prescription; Discontinued
ATC Code D07AD01
DrugBank ID DB11750
KEGG ID D07715
MeSH ID D002990
PubChem ID 5311051
TTD Drug ID D0FL5V
NDC Product Code Not Available
Synonyms Clobetasol | Clofenazon | Clobetasol Propionate | Clobetasol 17-Propionate | Clobetasol 17 Propionate | Clobex | Cormax | OLUX | Dermovate | Embeline | Embeline E | Temovate
Chemical Information
Molecular Formula C22H28ClFO4
CAS Registry Number 25122-41-2
SMILES CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CCl)O)C)O)F)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Alopecia23.02.02.001--
Application site atrophy12.07.01.037; 08.02.01.037--Not Available
Application site irritation12.07.01.003; 08.02.01.003--Not Available
Application site pain12.07.01.004; 08.02.01.004--Not Available
Application site pruritus12.07.01.005; 08.02.01.005; 23.03.12.004--Not Available
Application site reaction12.07.01.006; 08.02.01.006--Not Available
Atopy10.01.04.005--Not Available
Burning sensation17.02.06.001; 08.01.09.029--Not Available
Cushing's syndrome14.11.01.007; 05.01.01.001; 24.08.04.001; 19.07.03.002--Not Available
Dermatitis23.03.04.002--Not Available
Dermatitis acneiform23.02.01.004--
Dermatitis contact23.03.04.004; 12.03.01.040; 10.01.01.003--Not Available
Discomfort08.01.08.003--Not Available
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Dry skin23.03.03.001--
Endocrine disorder05.09.01.001--Not Available
Erythema23.03.06.001--Not Available
Eye irritation06.04.05.003--Not Available
Eye pain06.08.03.002--
Folliculitis23.09.04.007; 11.01.12.018--
Glycosuria20.02.01.005--
Hair colour changes23.02.06.001--
Headache17.14.01.001--
Hyperglycaemia14.06.02.002; 05.06.02.002--
Hypertrichosis23.02.04.002--
Hypoaesthesia17.02.06.023--Not Available
Infection11.01.08.002--Not Available
Influenza22.07.02.001; 11.05.03.001--Not Available
Instillation site pain12.07.01.008; 08.02.01.008--Not Available
Leukoderma23.05.02.001--Not Available
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