Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Citalopram
Drug ID BADD_D00475
Description Citalopram belongs to a class of antidepressant agents known as selective _serotonin-reuptake inhibitors_ (SSRIs) and is widely used to treat the symptoms of depression. Its chemical structure is unrelated to that of other SSRIs or of tricyclic, tetracyclic, or other prescribed antidepressants [FDA label]. Citalopram is also known as _Celexa_, and available in tablet and solution forms [FDA label]. This drug was initially approved by the FDA in 1998 [L5230].
Indications and Usage For the treatment of depression. Off-label indications include: treatment of mild dementia-associated agitation in nonpsychotic patients, smoking cessation, ethanol abuse, obsessive-compulsive disorder (OCD) in children, and diabetic neuropathy [FDA label].
Marketing Status Prescription
ATC Code N06AB04
DrugBank ID DB00215
KEGG ID D07704
MeSH ID D015283
PubChem ID 2771
TTD Drug ID D0Y5DO
NDC Product Code 69097-823; 42806-020; 70518-0561; 43063-385; 43353-112; 70518-2228; 65162-054; 67046-102; 71610-092; 0456-4020; 50090-5170; 69097-824; 68788-7899; 70518-2617; 43063-063; 70934-539; 65162-052; 54458-980; 69097-822; 70518-2553; 0054-0062; 52427-691; 60429-174; 67046-106; 76282-629; 61919-390; 76282-628; 50090-5172; 54458-889; 70518-2601; 70518-2671; 54458-981; 0378-6233; 71335-0541; 60429-173; 71610-412; 63850-3616; 65162-053; 0378-6231; 0456-4010; 42806-021; 76282-206; 68071-3034; 67046-101; 70518-0449; 60429-175; 70934-397; 43353-208; 50090-5175; 63629-6761; 0456-4040; 61919-389; 76282-208; 71610-422; 80425-0093; 76282-207; 0378-6232; 43353-091; 42806-019
Synonyms Citalopram | Cytalopram | Citalopram Hydrobromide | Lu-10-171 | Lu10171 | Seropram | Celexa
Chemical Information
Molecular Formula C20H21FN2O
CAS Registry Number 59729-33-8
SMILES CN(C)CCCC1(C2=C(CO1)C=C(C=C2)C#N)C3=CC=C(C=C3)F
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Poisoning and toxicityCytochrome P450 2D6P10635T57392Not Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Pulmonary artery stenosis congenital24.04.09.012; 22.06.03.007; 03.07.09.0080.000065%Not Available
Pulmonary valve stenosis congenital02.07.04.006; 03.07.05.0160.000333%Not Available
Respiratory tract malformation03.16.06.002; 22.02.07.0160.000250%Not Available
Sexual inhibition19.08.04.0080.000167%Not Available
Slow response to stimuli17.02.05.0630.000375%Not Available
Small for dates baby18.04.02.0020.001833%Not Available
Threatened labour18.07.01.0090.000167%Not Available
Transposition of the great vessels24.03.03.042; 03.07.08.009; 02.08.03.0050.000500%Not Available
Tremor neonatal18.04.04.012; 17.01.06.0100.000125%Not Available
Ventricular hypoplasia03.07.11.003; 02.08.01.0110.000250%Not Available
Vesicoureteric reflux20.03.05.0020.000167%Not Available
Violence-related symptom19.05.01.0220.000208%Not Available
Weight decrease neonatal18.04.02.0070.000083%Not Available
Umbilical cord abnormality18.04.14.0030.000083%Not Available
Hypertonia neonatal18.04.01.016; 15.05.04.019; 17.05.02.0170.000292%Not Available
Congenital choroid plexus cyst17.18.05.004; 16.09.05.004; 03.10.03.0040.000208%Not Available
Bladder trabeculation20.03.01.0200.000208%Not Available
Aorta hypoplasia24.03.03.018; 03.07.08.0020.000208%Not Available
Neonatal hypotension24.06.03.014; 18.04.07.0080.000167%Not Available
Live birth18.08.02.0070.000125%Not Available
Cervix haematoma uterine24.07.03.022; 21.06.01.0120.000208%Not Available
Hypothermia neonatal12.05.03.002; 08.05.01.007; 18.04.06.0040.000208%Not Available
Congenital pulmonary hypertension22.11.01.006; 18.04.09.005; 03.16.06.0010.000375%Not Available
Congenital hepatomegaly09.01.05.009; 03.19.01.0020.000043%Not Available
Meconium in amniotic fluid18.05.01.0070.000125%Not Available
Congenital pulmonary valve atresia03.07.05.009; 02.07.04.0030.000083%Not Available
Abortion late18.01.01.0040.000208%Not Available
Abscess jaw15.02.05.004; 11.01.01.0050.000125%Not Available
Neonatal pneumonia22.07.01.012; 18.04.12.004; 11.01.09.0170.000083%Not Available
IIIrd nerve paresis06.05.02.019; 17.04.02.0060.000083%Not Available
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