Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Choriogonadotropin alfa
Drug ID BADD_D00457
Description Recombinant human chorionic gonadotropin with 2 subunits, alpha = 92 residues, beta = 145 residues, each with N-and O-linked carbohydrate moieties linked to ASN-52 and ASN-78 (on alpha subunit) and ASN-13, ASN-30, SER-121, SER-127, SER-132 and SER-138 (on beta subunit). The primary structure of the alpha-chain of r-hCG is identical to that of the alpha-chain of hCG, FSH and LH.
Indications and Usage For the treatment of female infertility
Marketing Status Prescription; Discontinued
ATC Code G03GA08
DrugBank ID DB00097
KEGG ID D03478
MeSH ID D006063
PubChem ID Not Available
TTD Drug ID D00TTS
NDC Product Code 0052-0315; 50090-5923; 12860-0315; 44087-1150; 69443-315
Synonyms Chorionic Gonadotropin | Gonadotropin, Chorionic | Choriogonadotropin | Choriogonin | Pregnyl | Chorulon | Gonabion | Biogonadil | Chorionic Gonadotropin, Human | Gonadotropin, Human Chorionic | Human Chorionic Gonadotropin | HCG (Human Chorionic Gonadotropin)
Chemical Information
Molecular Formula Not Available
CAS Registry Number 177073-44-8
SMILES Not Available
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Metrorrhagia21.01.01.006--Not Available
Multiple congenital abnormalities03.02.01.003--Not Available
Mycoplasmal postpartum fever21.14.04.002; 11.10.01.001--Not Available
Nausea07.01.07.001--
Ovarian cyst21.11.01.002; 16.04.03.001--Not Available
Ovarian enlargement21.11.02.001--Not Available
Ovarian hyperstimulation syndrome21.11.02.007; 05.05.01.013--Not Available
Pain08.01.08.004--
Paraesthesia17.02.06.005--
Peritoneal haemorrhage24.07.02.016; 07.07.02.001--Not Available
Pharyngitis07.05.07.004; 22.07.03.004; 11.01.13.003--
Premature labour18.07.01.002--Not Available
Pruritus23.03.12.001--
Pyrexia08.05.02.003--
Rash23.03.13.001--Not Available
Thrombocytopenia01.08.01.002--Not Available
Upper respiratory tract infection22.07.03.011; 11.01.13.009--
Urinary incontinence20.02.02.010; 17.05.01.008--
Urinary tract infection11.01.14.004; 20.08.02.001--
Uterine disorder21.07.01.006--Not Available
Vaginal discharge21.08.02.002--
Vaginal haemorrhage24.07.03.005; 21.08.01.001--
Vaginal infection21.14.02.002; 11.01.10.002--
Vomiting07.01.07.003--
Vulvovaginal discomfort21.08.02.005--Not Available
Affect lability19.04.01.001--Not Available
Hot flush24.03.01.005; 21.02.02.001; 08.01.03.027--
Pulmonary vascular disorder24.03.08.003; 22.06.03.002--Not Available
Ovarian neoplasm16.12.06.001; 21.11.01.005--Not Available
Procedural pain08.01.08.009; 12.02.05.007--Not Available
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