Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Chlorzoxazone
Drug ID BADD_D00449
Description A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)
Indications and Usage For the relief of discomfort associated with acute painful musculoskeletal conditions.
Marketing Status Prescription; Discontinued
ATC Code M03BB03
DrugBank ID DB00356
KEGG ID D00771
MeSH ID D002753
PubChem ID 2733
TTD Drug ID D08ZEB
NDC Product Code 0591-2520; 53002-5760; 72319-168; 55289-633; 63629-1999; 0093-9142; 16571-726; 68462-725; 45865-434; 59651-306; 70518-0496; 68025-046; 51862-340; 51862-338; 69499-330; 13811-717; 42494-426; 61919-478; 63629-2000; 49999-044; 70954-085; 72319-169; 71335-2009; 68462-724; 63629-9158; 70966-0019; 46016-9522; 68025-047; 60760-479; 60760-619; 52817-231; 0093-9141; 50090-0315; 55700-951; 63629-1586; 42494-425; 51862-339; 73007-013; 70518-2053; 42494-428; 71335-1914; 54871-0001; 16571-727; 58159-030; 50090-0316; 63187-317; 52817-230; 24470-923; 43235-0005; 76055-0034; 0254-2005; 16571-725; 0254-2053; 13811-718
Synonyms Chlorzoxazone | Parafon | Parafon Forte DSC | Paraflex
Chemical Information
Molecular Formula C7H4ClNO2
CAS Registry Number 95-25-0
SMILES C1=CC2=C(C=C1Cl)NC(=O)O2
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Anaphylactic reaction24.06.03.006; 10.01.07.001--
Anaphylactic shock24.06.02.004; 10.01.07.002--Not Available
Angioedema10.01.05.009; 23.04.01.001--Not Available
Chromaturia20.02.01.002--
Dermatitis23.03.04.002--Not Available
Discomfort08.01.08.003--Not Available
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Dyspepsia07.01.02.001--
Ecchymosis24.07.06.002; 23.06.01.001; 01.01.03.001--Not Available
Feeling abnormal08.01.09.014--Not Available
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal haemorrhage24.07.02.009; 07.12.02.001--Not Available
Malaise08.01.01.003--
Petechiae24.07.06.004; 23.06.01.003; 01.01.03.002--Not Available
Rash23.03.13.001--Not Available
Somnolence19.02.05.003; 17.02.04.006--
Ill-defined disorder08.01.03.049--Not Available
Device stimulation issue27.01.02.005--Not Available
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