| Pharmaceutical Information |
| Drug Name |
Chlorothiazide |
| Drug ID |
BADD_D00442 |
| Description |
A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p812) |
| Indications and Usage |
Chlorothiazide is indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. It is also indicated in the management of hypertension either as the sole therapeutic agent or to enhance the effectiveness of other antihypertensive drugs in the more severe forms of hypertension. |
| Marketing Status |
Prescription; Discontinued |
| ATC Code |
C03AA04 |
| DrugBank ID |
DB00880
|
| KEGG ID |
D00519
|
| MeSH ID |
D002740
|
| PubChem ID |
2720
|
| TTD Drug ID |
D0M9WM
|
| NDC Product Code |
38779-3147; 65649-311; 12828-0005; 42419-007; 59605-1745; 33656-0012; 62756-439 |
| Synonyms |
Chlorothiazide |
|
| Chemical Information |
| Molecular Formula |
C7H6ClN3O4S2 |
| CAS Registry Number |
58-94-6 |
| SMILES |
C1=C2C(=CC(=C1Cl)S(=O)(=O)N)S(=O)(=O)N=CN2 |
| Chemical Structure |
|
|
| ADR Related Proteins Induced by Drug |
| ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
| Not Available | Not Available | Not Available | Not Available | Not Available |
|
| ADRs Induced by Drug |
|
| ADR Term |
ADReCS ID |
ADR Frequency (FAERS)
|
ADR Severity Grade (FAERS)
|
ADR Severity Grade (CTCAE)
|
| Renal impairment | 20.01.03.010 | - | - | Not Available |
|
|
|
