Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Chenodiol
Drug ID BADD_D00426
Description Chenodeoxycholic acid (or Chenodiol) is an epimer of ursodeoxycholic acid (DB01586). Chenodeoxycholic acid is a bile acid naturally found in the body. It works by dissolving the cholesterol that makes gallstones and inhibiting production of cholesterol in the liver and absorption in the intestines, which helps to decrease the formation of gallstones. It can also reduce the amount of other bile acids that can be harmful to liver cells when levels are elevated.
Indications and Usage Chenodiol is indicated for patients with radiolucent stones in well-opacifying gallbladders, in whom selective surgery would be undertaken except for the presence of increased surgical risk due to systemic disease or age. Chenodiol will not dissolve calcified (radiopaque) or radiolucent bile pigment stones.
Marketing Status Prescription; Discontinued
ATC Code A05AA01
DrugBank ID DB06777
KEGG ID D00163
MeSH ID D002635
PubChem ID 10133
TTD Drug ID D03ZTE
NDC Product Code 68974-876
Synonyms Chenodeoxycholic Acid | Acid, Chenodeoxycholic | Chenique Acid | Acid, Chenique | Gallodesoxycholic Acid | Acid, Gallodesoxycholic | Henohol | Chenic Acid | Acid, Chenic | Chenodiol | Chenodeoxycholate | Chenofalk | Chenophalk | Sodium Chenodeoxycholate | Chenodeoxycholate, Sodium | Quenocol | Chenix | Quenobilan
Chemical Information
Molecular Formula C24H40O4
CAS Registry Number 474-25-9
SMILES CC(CCC(=O)O)C1CCC2C1(CCC3C2C(CC4C3(CCC(C4)O)C)O)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Abdominal pain upper07.01.05.003--
Alanine aminotransferase increased13.03.01.003--
Blood cholesterol increased13.12.01.002--
Blood triglycerides decreased13.12.03.003--Not Available
Cholecystectomy25.09.01.001--Not Available
Cholestasis09.01.01.001--Not Available
Constipation07.02.02.001--
Diarrhoea07.02.01.001--
Dyspepsia07.01.02.001--
Flatulence07.01.04.002--
Gastrointestinal pain07.01.05.005--
Low density lipoprotein increased13.12.01.005--Not Available
Micturition urgency20.02.02.006--
Muscle spasms15.05.03.004--
Nausea07.01.07.001--
Vomiting07.01.07.003--
White blood cell count decreased13.01.06.012--
Emotional distress19.04.02.008--Not Available
Epigastric discomfort07.01.02.004--Not Available
Decreased appetite14.03.01.005; 08.01.09.028--
Hepatic lesion09.01.08.005--Not Available
The 1th Page    1    Total 1 Pages