Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Cefuroxime axetil
Drug ID BADD_D00408
Description Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.
Indications and Usage For the treatment of many different types of bacterial infections such as bronchitis, sinusitis, tonsillitis, ear infections, skin infections, gonorrhea, and urinary tract infections.
Marketing Status Prescription; Discontinued
ATC Code J01DC02; S01AA27
DrugBank ID DB01112
KEGG ID D00914
MeSH ID C040738
PubChem ID 5361467
TTD Drug ID Not Available
NDC Product Code 67877-216; 65862-700; 64679-920; 65862-699; 65862-505; 60429-657; 61788-1000; 16714-400; 65862-339; 50090-0781; 57237-058; 70518-2694; 64679-921; 43063-584; 65862-698; 64679-922; 57237-059; 63187-991; 61919-044; 68180-303; 61919-747; 43063-656; 70934-088; 70518-3215; 43063-623; 50090-4153; 51407-334; 60687-272; 50090-2157; 50090-2159; 72789-035; 16714-401; 68071-1637; 50090-2158; 51407-333; 68180-302; 53002-2670; 43063-657; 68071-4947; 53002-2750; 60429-656; 55289-385; 67877-215
Synonyms cefuroxime axetil | acetoxyethylcefuroxime | cefuroxime 1-acetoxyethyl ester | Ceftin | Zinnat | CCI 15641 | CCI-15641
Chemical Information
Molecular Formula C20H22N4O10S
CAS Registry Number 64544-07-6
SMILES CC(OC(=O)C)OC(=O)C1=C(CSC2N1C(=O)C2NC(=O)C(=NOC)C3=CC=CO3)COC(=O)N
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Agitation19.06.02.001; 17.02.05.012--
Agranulocytosis01.02.03.001--Not Available
Alanine aminotransferase increased13.03.01.003--
Anaphylactic reaction24.06.03.006; 10.01.07.001--
Anaphylactic shock24.06.02.004; 10.01.07.002--Not Available
Angioedema23.04.01.001; 10.01.05.009--Not Available
Aplastic anaemia01.03.03.002--Not Available
Arthralgia15.01.02.001--
Blood bilirubin increased13.03.01.008--
Blood creatinine increased13.13.01.004--
Blood lactate dehydrogenase increased13.04.02.002--
Blood urea increased13.13.01.006--Not Available
Body temperature increased13.15.01.001--Not Available
Chest discomfort22.02.08.001; 08.01.08.019; 02.02.02.009--Not Available
Chest pain08.01.08.002; 02.02.02.011; 22.02.08.003--Not Available
Chills15.05.03.016; 08.01.09.001--
Cholestasis09.01.01.001--Not Available
Cough22.02.03.001--
Dermatitis23.03.04.002--Not Available
Dermatitis diaper23.03.04.005--Not Available
Diarrhoea07.02.01.001--
Disability26.01.01.003--Not Available
Dizziness02.01.02.004; 24.06.02.007; 17.02.05.003--
Dyspepsia07.01.02.001--
Dyspnoea22.02.01.004; 02.01.03.002--
Dysuria20.02.02.002--
Eosinophilia01.02.04.001--
Erythema23.03.06.001--Not Available
Erythema multiforme23.03.01.003; 10.01.03.015--
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