Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Cefuroxime
Drug ID BADD_D00407
Description Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.
Indications and Usage For the treatment of many different types of bacterial infections such as bronchitis, sinusitis, tonsillitis, ear infections, skin infections, gonorrhea, and urinary tract infections.
Marketing Status approved
ATC Code J01DC02; S01AA27
DrugBank ID DB01112
KEGG ID D00262
MeSH ID D002444
PubChem ID 41375
TTD Drug ID D0Y2IE
NDC Product Code 0143-9567; 0143-9569; 0143-9976; 0143-9568; 0143-9977; 0143-9979
UNII O1R9FJ93ED
Synonyms Cefuroxime | Cephuroxime | Zinacef | Ketocef
Chemical Information
Molecular Formula C16H16N4O8S
CAS Registry Number 55268-75-2
SMILES CON=C(C1=CC=CO1)C(=O)NC2C3N(C2=O)C(=C(CS3)COC(=O)N)C(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Blood urea increased13.13.01.006--Not Available
Body temperature increased13.15.01.001--Not Available
Bradycardia02.03.02.0020.000429%Not Available
Brain hypoxia24.04.06.022; 22.02.02.010; 17.08.02.0090.000286%Not Available
Bronchitis22.07.01.001; 11.01.09.001--
Bronchospasm22.03.01.004; 10.01.03.0120.000644%
Burning sensation17.02.06.001; 08.01.09.0290.000286%Not Available
Capillary leak syndrome24.06.03.001; 08.01.07.0120.000143%
Cardiac arrest02.03.04.0010.001359%
Cardio-respiratory arrest22.02.06.007; 02.03.04.0020.000215%Not Available
Cardiovascular disorder24.03.02.009; 02.11.01.0100.000501%Not Available
Chest discomfort22.12.02.002; 08.01.08.019; 02.02.02.0090.000501%Not Available
Chest pain22.12.02.003; 08.01.08.002; 02.02.02.0110.000858%Not Available
Chills15.05.03.016; 08.01.09.0010.000672%
Cholelithiasis09.03.01.0020.000143%Not Available
Cholestasis09.01.01.0010.000143%Not Available
Circulatory collapse24.06.02.0010.000501%Not Available
Cold sweat23.02.03.002; 08.01.03.0240.000215%Not Available
Colitis07.08.01.001--
Colitis ischaemic07.08.01.004; 24.04.08.0120.000215%Not Available
Colour blindness acquired06.02.09.0020.001946%Not Available
Coma17.02.09.0010.000286%Not Available
Complications of transplanted liver12.02.09.014; 09.01.08.011--Not Available
Confusional state19.13.01.001; 17.02.03.005--
Conjunctival haemorrhage06.07.01.001; 24.07.05.0010.000286%Not Available
Conjunctival oedema06.04.01.0010.000315%Not Available
Corneal deposits06.06.03.0020.000286%Not Available
Corneal oedema06.04.02.0010.006724%Not Available
Corneal opacity06.06.03.0050.001860%Not Available
Coronary artery stenosis12.02.01.037; 24.04.04.017; 02.02.01.0100.000143%Not Available
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ADReCS-Target
Drug Name ADR Term Target
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