| Drug Name |
Ceftriaxone |
| Drug ID |
BADD_D00405 |
| Description |
Ceftriaxone is a broad-spectrum third-generation cephalosporin antibiotic.[A215582] It has a very long half-life compared to other cephalosporins and is high penetrable into the meninges[A215582], eyes[A215647], and inner ear[A215627]. Ceftriaxone has broader and stronger gram-negative coverage then first or second-generation cephalosporins, but worse activity against methicillin-susceptible S.aureus. Ceftriaxone is a commonly used antimicrobial due to its good activity against multi-drug resistant Enterobacteriaceae, its relatively safe adverse effect profile, and its long half-life which allows for the convenience of daily or twice-daily dosing.[A215582] |
| Indications and Usage |
For the treatment of the infections (respiratory, skin, soft tissue, UTI, ENT) caused by S. pneumoniae, H. influenzae, staphylococci, S. pyogenes (group A beta-hemolytic streptococci), E. coli, P. mirabilis, Klebsiella sp, coagulase-negative staph |
| Marketing Status |
Prescription; Discontinued |
| ATC Code |
J01DD04 |
| DrugBank ID |
DB01212
|
| KEGG ID |
D07659
|
| MeSH ID |
D002443
|
| PubChem ID |
5479530
|
| TTD Drug ID |
D07ACT
|
| NDC Product Code |
66794-214; 71205-593; 68071-4713; 44567-702; 66794-215; 70518-3355; 68180-633; 0143-9859; 50090-0945; 63187-435; 66794-213; 64679-702; 64679-701; 25021-106; 0143-9678; 68180-622; 25021-105; 66794-212; 25021-107; 0264-3155; 44567-700; 64679-703; 66794-211; 44567-703; 0143-9856; 71205-117; 0143-9858; 68071-4715; 72572-061; 68180-611; 68071-4304; 64679-983; 68071-4303; 44567-701; 0264-3153; 0143-9857; 63323-346; 68180-644; 72572-062; 50090-2628 |
| Synonyms |
Ceftriaxone | Ceftriaxon | Cefatriaxone | Ceftriaxone, Disodium Salt, Hemiheptahydrate | Ceftrex | Ceftriaxon Curamed | Ceftriaxon Hexal | Ceftriaxona Andreu | Ceftriaxona LDP Torlan | Ceftriaxone Irex | Ceftriaxone Sodium | Ceftriaxone Sodium, Anhydrous | Anhydrous Ceftriaxone Sodium | Lendacin | Longacef | Longaceph | Ro13-9904 | Ro13 9904 | Ro139904 | Ro-13-9904 | Ro 13-9904 | Ro 13 9904 | Ro 139904 | Rocephin | Rocefalin | Rocephine | Rocefin | Tacex | Terbac | Ceftriaxone, Disodium Salt | Benaxona | Cefaxona |
