Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Cefaclor
Drug ID BADD_D00378
Description Semisynthetic, broad-spectrum antibiotic derivative of cephalexin.
Indications and Usage For the treatment of certain infections caused by bacteria such as pneumonia and ear, lung, skin, throat, and urinary tract infections.
Marketing Status Prescription; Discontinued
ATC Code J01DC04
DrugBank ID DB00833
KEGG ID D00256
MeSH ID D002433
PubChem ID 51039
TTD Drug ID D0PW7C
NDC Product Code 0093-1087; 0143-9985; 61442-172; 63629-1007; 23594-375; 61442-171; 23594-250; 0143-9986; 50090-1602; 23594-125
Synonyms Cefaclor | Cefaclor Anhydrous | Keclor | 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((aminophenylacetyl)amino)-3-chloro-8-oxo-, (6R-(6alpha,7beta(R*)))- | S-6472 | S 6472 | S6472 | Ceclor | Cefaclor Monohydrate | Lilly 99638
Chemical Information
Molecular Formula C15H14ClN3O4S
CAS Registry Number 53994-73-3
SMILES C1C(=C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)N)C(=O)O)Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Chills15.05.03.016; 08.01.09.001--
Cholestasis09.01.01.001--Not Available
Colitis07.08.01.001--
Confusional state19.13.01.001; 17.02.03.005--
Conjunctivitis11.01.06.012; 06.04.01.002--
Constipation07.02.02.001--
Cough22.02.03.001--
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Discomfort08.01.08.003--Not Available
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.0040.000213%
Drug eruption23.03.05.001; 10.01.01.005; 08.01.06.0150.000319%Not Available
Drug hypersensitivity10.01.01.0010.000852%Not Available
Dysmenorrhoea21.01.01.002--
Dyspepsia07.01.02.001--
Dyspnoea02.01.03.002; 22.02.01.004--
Dysuria20.02.02.002--
Ear pain04.03.01.003--
Eosinophilia01.02.04.001--
Epistaxis24.07.01.005; 22.04.03.001--
Erythema multiforme23.03.01.003; 10.01.03.015--
Face oedema08.01.07.003; 23.04.01.004; 10.01.05.002--
Feeling abnormal08.01.09.014--Not Available
Flatulence07.01.04.002--
Gamma-glutamyltransferase increased13.03.01.011--
Gastritis07.08.02.001--
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal pain07.01.05.005--
Haematuria24.07.01.047; 20.02.01.006--
Haemoglobin13.01.05.018--Not Available
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