Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Bupivacaine hydrochloride
Drug ID BADD_D00309
Description Bupivacaine is a widely used local anesthetic agent.
Indications and Usage For the production of local or regional anesthesia or analgesia for surgery, for oral surgery procedures, for diagnostic and therapeutic procedures, and for obstetrical procedures.
Marketing Status Prescription; Discontinued
ATC Code N01BB01
DrugBank ID DB00297
KEGG ID D01450
MeSH ID D002045
PubChem ID 64737
TTD Drug ID D0A0FL
NDC Product Code 59923-718; 55579-397; 0404-9946; 63275-9993; 76420-008; 0143-9334; 0409-1610; 0409-1165; 73293-0002; 0409-1159; 0143-9330; 52584-465; 0409-1160; 52584-559; 0409-1162; 63323-464; 0143-9328; 0409-1163; 0409-1560; 59923-717; 38779-0524; 59923-720; 0409-1587; 70518-2360; 52584-466; 0143-9333; 0143-9335; 0404-9947; 63323-466; 71277-0126; 55150-171; 70529-007; 55154-6970; 55150-170; 68788-8114; 0409-1582; 59923-719; 52584-467; 0409-1559; 0404-9827; 76420-018; 55150-168; 62991-2014; 0143-9329; 0395-8050; 66064-1031; 51662-1396; 55150-249; 70529-008; 0404-9826; 52932-0729; 36000-092; 71872-7133; 52584-560; 52584-160; 70529-006; 55150-250; 71872-7270; 55150-172; 52584-163; 55150-167; 63323-467; 0404-9945; 66206-0126; 71872-7217; 12651-111; 55150-169; 70529-005; 63323-465; 0143-9331; 79572-004; 49452-1313; 63323-472; 76420-230; 61876-0726; 0143-9332; 51927-2358; 50090-4516; 17381-074
Synonyms Bupivacaine | 1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide | Marcain | Bupivacain Janapharm | Bupivacain-RPR | Bupivacain RPR | Bupivacaina Braun | Carbostesin | Bupivacaine Carbonate | Bupivacaine Hydrochloride | Bupivacaine Monohydrochloride, Monohydrate | Buvacaina | Dolanaest | Sensorcaine | Svedocain Sin Vasoconstr | Marcaine | Bupivacaine Anhydrous
Chemical Information
Molecular Formula C18H29ClN2O
CAS Registry Number 18010-40-7
SMILES CCCCN1CCCCC1C(=O)NC2=C(C=CC=C2C)C.Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Muscular weakness17.05.03.005; 15.05.06.001--
Nausea07.01.07.001--
Paraesthesia17.02.06.005--
Paralysis17.01.04.004--Not Available
Pruritus23.03.12.001--
Respiratory paralysis22.02.06.003; 17.01.04.010--Not Available
Restlessness19.11.02.002; 17.02.05.021--
Sexual dysfunction21.03.02.003; 19.08.05.002--Not Available
Sneezing22.02.05.011--
Spinal anaesthesia25.01.03.001--Not Available
Syncope24.06.02.012; 17.02.04.008; 02.01.02.008--
Tachycardia02.03.02.007--Not Available
Tinnitus17.04.07.004; 04.04.01.002--
Tremor17.01.06.002--
Urinary incontinence20.02.02.010; 17.05.01.008--
Urinary retention20.02.02.011--
Urticaria23.04.02.001; 10.01.06.001--
Ventricular arrhythmia02.03.04.006--
Ventricular fibrillation02.03.04.008--
Ventricular tachycardia02.03.04.010--
Vision blurred17.17.01.010; 06.02.06.007--
Vomiting07.01.07.003--
CSF test abnormal13.07.02.005--Not Available
Anaesthetic complication12.02.12.002--Not Available
Myocardial depression02.04.02.015--Not Available
Anal incontinence17.05.01.021; 07.01.06.029--
The 2th Page    First    Pre   2    Total 2 Pages