Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Budesonide
Drug ID BADD_D00306
Description Budesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis.[A188529,A188532] Budesonide was granted FDA approval on 14 February 1994.[L10598]
Indications and Usage The oral capsule is used for the treatment of mild to moderate active Crohn's disease. The oral tablet is used for induction of remission in patients with active, mild to moderate ulcerative colitis. The oral inhalation formulation is used for the treatment of asthma, non-infectious rhinitis (including hay fever and other allergies), and for treatment and prevention of nasal polyposis.
Marketing Status Prescription; OTC; Discontinued
ATC Code A07EA06; D07AC09; R01AD05; R03BA02
DrugBank ID DB01222
KEGG ID D00246
MeSH ID D019819
PubChem ID 5281004
TTD Drug ID D0Y7IU
NDC Product Code 0574-9850; 60505-6129; 0093-6815; 60687-596; 46122-389; 38779-3097; 21130-710; 60870-0466; 0093-6817; 0093-6816; 55566-1002; 49076-6111; 0363-0048; 51407-366; 0904-7166; 65162-778; 52128-133; 0591-2510; 0186-1988; 0186-1990; 51862-580; 0378-4500; 0487-9601; 47335-631; 63629-8294; 0781-7516; 15308-0100; 51508-004; 68788-7290; 0378-7155; 16714-018; 65089-0005; 52221-117; 76282-641; 81749-004; 49452-1292; 46439-8719; 60505-0839; 16714-829; 55154-4849; 65089-0024; 69097-318; 0574-9855; 68382-720; 65649-651; 76282-640; 38779-0198; 69097-321; 16714-020; 0115-1687; 76282-642; 55566-1020; 69842-001; 60429-264; 64918-0205; 49927-0004; 0186-1989; 10695-124; 50090-2239; 50580-646; 60505-6194; 71052-270; 51079-020; 51407-128; 68682-309; 0186-0916; 49452-1291; 16714-019; 68788-7314; 70771-1075; 68012-309; 0781-7517; 63592-0187; 0487-9701; 11822-1700; 50546-580; 63190-0060; 49035-703; 53183-6310; 53104-7617; 68743-309; 0781-7515; 73377-076; 47335-633; 0115-1689; 64918-0204; 69097-319; 0536-1112; 66412-0393; 51552-1365; 46439-8737; 68981-017; 47335-632; 0186-0917; 64980-255
Synonyms Budesonide | Budesonide, (S)-Isomer | Pulmicort | Rhinocort | Budesonide, (R)-Isomer | Horacort
Chemical Information
Molecular Formula C25H34O6
CAS Registry Number 51333-22-3
SMILES CCCC1OC2CC3C4CCC5=CC(=O)C=CC5(C4C(CC3(C2(O1)C(=O)CO)C)O)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Myopathy15.05.05.0010.000406%Not Available
Nasal congestion22.04.04.001--
Nasal oedema22.04.03.0120.001016%Not Available
Nasal septum perforation22.04.03.003--Not Available
Nasopharyngitis22.07.03.002; 11.01.13.0020.001219%Not Available
Nausea07.01.07.001--
Neck pain15.03.04.009--
Necrosis24.04.02.006; 08.03.03.0010.000609%Not Available
Necrosis ischaemic24.04.02.018--Not Available
Neoplasm16.16.02.0010.000106%Not Available
Neoplasm malignant16.16.01.001--Not Available
Nervous system disorder17.02.10.001--Not Available
Nervousness19.06.02.0030.000609%Not Available
Neutropenia01.02.03.004--Not Available
Nightmare19.02.03.0030.000406%Not Available
Nocturia20.02.03.001--Not Available
Non-Hodgkin's lymphoma01.17.01.001; 16.35.01.0010.000406%Not Available
Ocular hyperaemia06.04.05.0040.000406%Not Available
Oedema14.05.06.010; 08.01.07.0060.001016%Not Available
Oedema peripheral14.05.06.011; 08.01.07.007; 02.05.04.007--
Oesophageal candidiasis11.03.03.008; 07.19.06.0010.001625%Not Available
Oesophageal ulcer07.04.05.0020.000609%
Oligohydramnios18.05.01.0010.000406%Not Available
Oral candidiasis11.03.03.004; 07.05.07.0010.000406%Not Available
Osteonecrosis24.04.05.004; 15.02.04.0070.000406%
Osteoporosis15.02.03.002; 14.04.04.002--
Otitis media11.01.05.004; 04.05.01.001--
Oxygen saturation decreased13.02.01.0040.001828%Not Available
Pain08.01.08.004--
Pain in extremity15.03.04.010--
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