Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Bethanechol chloride
Drug ID BADD_D00266
Description Bethanechol is a synthetic ester that was initially synthesized in 1935.[A232905,L32539] As a cholinergic agent, bethanechol is similar in structure and pharmacological function to acetylcholine and is used in specific cases when stimulation of the parasympathetic nervous system is necessary.[A232905,L32539] For example, bethanechol is readily used to treat postoperative or postpartum urinary retention. An advantage of bethanechol is that in contrast to acetylcholine, bethanechol is not degraded by cholinesterase allowing its effects to be longer-lasting.[L32539]
Indications and Usage Bethanechol is indicated for the treatment of acute, functional postpartum and postoperative urinary retention. It is also indicated for the treatment of neurogenic atony of the bladder with retention.[A226320,L32539]
Marketing Status approved
ATC Code N07AB02
DrugBank ID DB01019
KEGG ID D01000
MeSH ID D018723
PubChem ID 11548
TTD Drug ID D07ZTO
NDC Product Code 65162-572; 0527-1356; 0832-0510; 0832-0513; 0904-6178; 65732-121; 63629-2025; 53746-572; 63629-2022; 65162-573; 0527-1332; 53746-573; 53746-574; 17381-207; 60687-689; 0832-0511; 0832-0512; 63629-9293; 65162-571; 0527-1340; 63629-2023; 68084-365; 0527-1329; 53746-571; 60687-700; 63629-2024; 68084-704; 65162-574
UNII H4QBZ2LO84
Synonyms Bethanechol | Bethanecol | Bethanechol Chloride | Chloride, Bethanechol | Duvoid | Myotonine | Myocholine | PMS-Bethanechol Chloride | PMS Bethanechol Chloride | Urocarb | Myotonachol | Urecholine | Myo Hermes | Hermes, Myo
Chemical Information
Molecular Formula C7H17ClN2O2
CAS Registry Number 590-63-6
SMILES CC(C[N+](C)(C)C)OC(=O)N.[Cl-]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal pain07.01.05.002--
Asthma22.03.01.002; 10.01.03.010--Not Available
Blood pressure decreased13.14.03.002--Not Available
Blood pressure increased13.14.03.005--Not Available
Bronchospasm10.01.03.012; 22.03.01.004--
Diarrhoea07.02.01.001--
Eructation07.01.02.003--
Feeling hot08.01.09.009--Not Available
Flushing24.03.01.002; 23.06.05.003; 08.01.03.025--
Headache17.14.01.001--
Hyperhidrosis23.02.03.004; 08.01.03.028--
Lacrimation increased06.08.02.004--
Malaise08.01.01.003--
Micturition urgency20.02.02.006--
Miosis17.02.11.002; 06.05.03.003--Not Available
Nausea07.01.07.001--
Salivary hypersecretion07.06.01.009--Not Available
Seizure17.12.03.001--
Tachycardia02.03.02.007--Not Available
Vasoconstriction24.04.03.008; 23.06.05.007--Not Available
Gastrointestinal sounds abnormal07.01.01.002--Not Available
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