Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Bethanechol chloride
Drug ID BADD_D00266
Description Bethanechol is a synthetic ester that was initially synthesized in 1935.[A232905,L32539] As a cholinergic agent, bethanechol is similar in structure and pharmacological function to acetylcholine and is used in specific cases when stimulation of the parasympathetic nervous system is necessary.[A232905,L32539] For example, bethanechol is readily used to treat postoperative or postpartum urinary retention. An advantage of bethanechol is that in contrast to acetylcholine, bethanechol is not degraded by cholinesterase allowing its effects to be longer-lasting.[L32539]
Indications and Usage For the treatment of acute postoperative and postpartum nonobstructive (functional) urinary retention and for neurogenic atony of the urinary bladder with retention.
Marketing Status Prescription; Discontinued
ATC Code N07AB02
DrugBank ID DB01019
KEGG ID D01000
MeSH ID D018723
PubChem ID 11548
NDC Product Code 63629-2022; 63629-2025; 0832-0513; 63629-2023; 65162-573; 0832-0511; 51293-648; 51293-647; 0527-1356; 0527-1329; 17381-207; 68084-365; 0832-0510; 51293-645; 65162-571; 65162-572; 43744-031; 0832-0512; 0904-6178; 68084-704; 0527-1332; 65162-574; 65732-121; 72969-006; 0527-1340; 63629-2024; 51293-646; 71335-0846
Synonyms Bethanechol | Bethanecol | Bethanechol Chloride | Chloride, Bethanechol | Duvoid | Myotonine | Myocholine | PMS-Bethanechol Chloride | PMS Bethanechol Chloride | Urocarb | Myotonachol | Urecholine | Myo Hermes | Hermes, Myo
Chemical Information
Molecular Formula C7H17ClN2O2
CAS Registry Number 590-63-6
SMILES CC(C[N+](C)(C)C)OC(=O)N.[Cl-]
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal pain07.01.05.002--
Asthma10.01.03.010; Available
Blood pressure decreased13.14.03.002--Not Available
Blood pressure increased13.14.03.005--Not Available
Feeling hot08.01.09.009--Not Available
Lacrimation increased06.08.02.004--
Micturition urgency20.02.02.006--
Miosis17.02.11.002; Available
Salivary hypersecretion07.06.01.009--Not Available
Tachycardia02.03.02.007--Not Available
Vasoconstriction23.06.05.007; Available
Gastrointestinal sounds abnormal07.01.01.002--Not Available
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