Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Bepridil
Drug ID BADD_D00254
Description A long-acting, non selective, calcium channel blocker with significant anti-anginal activity. The drug produces significant coronary vasodilation and modest peripheral effects. It has antihypertensive and selective anti-arrhythmia activities and acts as a calmodulin antagonist. It is no longer marketed in the United States, as it has been implicated in causing ventricular arrhythmias (ie. Torsade de pointes).
Indications and Usage For the treatment of hypertension, and chronic stable angina (classic effort-associated angina).
Marketing Status Discontinued
ATC Code C08EA02
DrugBank ID DB01244
KEGG ID D07520
MeSH ID D015764
PubChem ID 2351
TTD Drug ID D0Y4JJ
NDC Product Code Not Available
Synonyms Bepridil | Bepridil Monohydrochloride | Monohydrochloride, Bepridil | Vascor | Bedapin | Bepridil Monohydrochloride, alpha-Isomer | Bepridil Monohydrochloride, alpha Isomer | Monohydrochloride, alpha-Isomer Bepridil | Cordium | Unicordium | Bepridil, (+)-Isomer | Bepridil, (+-)-Isomer | Bepridil, (-)-Isomer | Bepridil, alpha-Isomer | Bepridil, alpha Isomer | CERM-1978 | CERM 1978 | CERM1978 | 1978-CERM | 1978 CERM | 1978CERM | Bepadin | Bepridil Monohydrochloride, Monohydrate
Chemical Information
Molecular Formula C24H34N2O
CAS Registry Number 64706-54-3
SMILES CC(C)COCC(CN(CC1=CC=CC=C1)C2=CC=CC=C2)N3CCCC3
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Vertigo17.02.12.002; 04.04.01.003--
Vision blurred17.17.01.010; 06.02.06.007--
Emotional distress19.04.02.008--Not Available
Musculoskeletal discomfort15.03.04.001--Not Available
Vasodilation procedure25.03.01.001--Not Available
Cardiac disorder02.01.01.003--Not Available
Decreased appetite14.03.01.005; 08.01.09.028--
Erectile dysfunction19.08.04.001; 21.03.01.007--
Respiratory tract infection22.07.07.001; 11.01.08.017--Not Available
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