| Pharmaceutical Information |
| Drug Name |
Benzydamine |
| Drug ID |
BADD_D00246 |
| Description |
Benzydamine (also known as Tantum Verde or Difflam), available as the hydrochloride salt, is a locally-acting nonsteroidal anti-inflammatory drug (NSAID) with local anaesthetic and analgesic properties. It is used topically for pain relief and anti-inflammatory treatment of the mouth, throat, or muscoskeletal system.
Although the indazole analogue benzydamine is a non-steroidal anti-inflammatory drug (NSAID), it has various physicochemical properties and pharmacologic activities that are different from those of traditional aspirin-like NSAIDs but facilitate benzydamine's mechanism of action as an effective locally-acting NSAID with local anaesthetic and analgesic properties. Moreover, unlike aspirin-like NSAIDs which are acids or metabolised to acids, benzydamine is in fact a weak base. |
| Indications and Usage |
When used as a topical cream, benzydamine may be employed to relieve symptoms associated with painful inflammatory conditions of the muscolo-skeletal system including acute inflammatory disorders such as myalgia and bursitis or traumatic conditions like sprains, strains, bruises, sore muscles, stiff joints, or even the after-effects of fractures. [ L1123] |
| Marketing Status |
Not Available |
| ATC Code |
A01AD02; G02CC03; M01AX07; M02AA05; R02AX03 |
| DrugBank ID |
DB09084
|
| KEGG ID |
D07516
|
| MeSH ID |
D001591
|
| PubChem ID |
12555
|
| TTD Drug ID |
D06FJO
|
| NDC Product Code |
Not Available |
| Synonyms |
Benzydamine | Benzidamine | Benzindamine | Novo-Benzydamine | Novo Benzydamine | Opalgyne | PMS-Benzydamine | PMS Benzydamine | Difflam | Rosalgin | Tantum Topico | Tantum | Sun-Benz | Sun Benz | Benzydamine Hydrochloride | Hydrochloride, Benzydamine | Benzydamine Monohydrochloride | Monohydrochloride, Benzydamine | Lonol | Ratio-Benzydamine | Ratio Benzydamine |
|
| Chemical Information |
| Molecular Formula |
C19H23N3O |
| CAS Registry Number |
642-72-8 |
| SMILES |
CN(C)CCCOC1=NN(C2=CC=CC=C21)CC3=CC=CC=C3 |
| Chemical Structure |
|
|
| ADR Related Proteins Induced by Drug |
| ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
| Not Available | Not Available | Not Available | Not Available | Not Available |
|
| ADRs Induced by Drug |
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