Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Benzphetamine
Drug ID BADD_D00242
Description A sympathomimetic agent with properties similar to dextroamphetamine. It is used in the treatment of obesity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1222)
Indications and Usage For the management of exogenous obesity as a short term adjunct (a few weeks) in a regimen of weight reduction based on caloric restriction
Marketing Status Discontinued
ATC Code Not Available
DrugBank ID DB00865
KEGG ID D07514
MeSH ID D001589
PubChem ID 5311017
TTD Drug ID D0T5UL
NDC Product Code Not Available
Synonyms Benzphetamine | Benzfetamine | Didrex
Chemical Information
Molecular Formula C17H21N
CAS Registry Number 156-08-1
SMILES CC(CC1=CC=CC=C1)N(C)CC2=CC=CC=C2
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Blood pressure increased13.14.03.005--Not Available
Cardiomyopathy02.04.01.001--Not Available
Depression19.15.01.001--
Diarrhoea07.02.01.001--
Dizziness17.02.05.003; 02.01.02.004; 24.06.02.007--
Dry mouth07.06.01.002--
Dysgeusia17.02.07.003; 07.14.03.001--
Gastrointestinal disorder07.11.01.001--Not Available
Headache17.14.01.001--
Hyperhidrosis23.02.03.004; 08.01.03.028--
Insomnia19.02.01.002; 17.15.03.002--
Myocardial ischaemia24.04.04.010; 02.02.02.008--Not Available
Nausea07.01.07.001--
Palpitations02.01.02.003--
Restlessness19.11.02.002; 17.02.05.021--
Tachycardia02.03.02.007--Not Available
Tremor17.01.06.002--
Urticaria23.04.02.001; 10.01.06.001--
Libido disorder21.03.02.006; 19.08.03.004--Not Available
Cardiac valve disease02.07.02.001--Not Available
Psychotic disorder19.03.01.002--
Device stimulation issue27.01.02.005--Not Available
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