Pharmaceutical Information |
Drug Name |
Becaplermin |
Drug ID |
BADD_D00216 |
Description |
Becaplermin is produced by recombinant DNA technology by insertion of the gene for the B chain of platelet derived growth factor (PDGF) into the yeast, Saccharomyces cerevisiae. Becaplermin has a molecular weight of approximately 25 KD and is a homodimer composed of two identical polypeptide chains that are bound together by disulfide bonds. |
Indications and Usage |
For topical treatment of skin ulcers (from diabetes) |
Marketing Status |
Prescription |
ATC Code |
A01AD08; D03AX06 |
DrugBank ID |
DB00102
|
KEGG ID |
D03065
|
MeSH ID |
D000077214
|
PubChem ID |
Not Available
|
TTD Drug ID |
D0T5QT
|
NDC Product Code |
63508-005; 50484-810 |
Synonyms |
Becaplermin | Platelet-Derived Growth Factor BB, Recombinant | Platelet Derived Growth Factor BB, Recombinant | rPDGF-BB | PDGF-BB | rhPDGF-BB | Platelet-Derived Growth Factor BB | Platelet Derived Growth Factor BB | Recombinant Platelet-Derived Growth Factor BB | Recombinant Platelet Derived Growth Factor BB | Regranex |
|
Chemical Information |
Molecular Formula |
Not Available |
CAS Registry Number |
165101-51-9 |
SMILES |
Not Available |
Chemical Structure |
|
|
ADR Related Proteins Induced by Drug |
ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
Not Available | Not Available | Not Available | Not Available | Not Available |
|
ADRs Induced by Drug |
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