| Pharmaceutical Information |
| Drug Name |
Bazedoxifene acetate |
| Drug ID |
BADD_D00215 |
| Description |
Bazedoxifene is a third generation selective estrogen receptor modulator (SERM), developed by Pfizer following the completion of their takeover of Wyeth Pharmaceuticals. In late 2013, Pfizer received approval for bazedoxifene as part of the combination drug DUAVEE in the prevention (not treatment) of postmenopausal osteoporosis. It is approved in the European Union (marketed in Italy and Spain) and Japan as monotherapy. In 2013, the combination product containing conjugated estrogens and bazedoxifene was approved by the FDA for the treatment of moderate to severe vasomotor symptoms associated with menopause, as well as the prevention of postmenopausal osteoporosis in women. |
| Indications and Usage |
Investigated for use/treatment in osteoporosis and menopause. |
| Marketing Status |
Not Available |
| ATC Code |
G03XC02 |
| DrugBank ID |
DB06401
|
| KEGG ID |
D03062
|
| MeSH ID |
C447119
|
| PubChem ID |
154256
|
| TTD Drug ID |
D0JY8T
|
| NDC Product Code |
55111-949 |
| Synonyms |
bazedoxifene | TSE 424 | TSE424 | TSE-424 | WAY-140424 | bazedoxifene acetate |
|
| Chemical Information |
| Molecular Formula |
C32H38N2O5 |
| CAS Registry Number |
198481-33-3 |
| SMILES |
CC1=C(N(C2=C1C=C(C=C2)O)CC3=CC=C(C=C3)OCCN4CCCCCC4)C5=CC=C(C=C5)O.CC(=O)O |
| Chemical Structure |
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|
| ADR Related Proteins Induced by Drug |
| ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
| Not Available | Not Available | Not Available | Not Available | Not Available |
|
| ADRs Induced by Drug |
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