| Drug Name |
Azelastine |
| Drug ID |
BADD_D00198 |
| Description |
Azelastine, a phthalazine derivative, is an antihistamine available as an intranasal spray for the treatment of allergic and vasomotor rhinitis and as an ophthalmic solution for the treatment of allergic conjunctivitis.[L8240,L8270] It is a racemic mixture, though there is no noted difference in pharmacologic activity between enantiomers, and was first granted FDA approval in 1996.[L8240,L8270] Azelastine is also available in combination with fluticasone propionate as a nasal spray marketed under the trade name Dymista™, which is indicated for the symptomatic treatment of seasonal allergic rhinitis in patients 6 years of age and older.[L8309] |
| Indications and Usage |
For the symptomatic treatment of seasonal allergic rhinitis and non-allergic rhinitis, as well as symptomatic relief of ocular itching associated with allergic conjunctivitis. |
| Marketing Status |
Prescription; Discontinued |
| ATC Code |
R01AC03; R06AX19; S01GX07 |
| DrugBank ID |
DB00972
|
| KEGG ID |
D07483
|
| MeSH ID |
C020976
|
| PubChem ID |
2267
|
| TTD Drug ID |
D00JVR
|
| NDC Product Code |
65162-676; 50090-3833; 42291-094; 67877-477 |
| Synonyms |
azelastine | 4-(p-chlorobenzyl)-2-(N-methylperhydroazepinyl-(4))-1-(2H)-phthalazinone | Allergodil | Astelin | azelastine hydrochloride | 4-((4-chlorophenyl)methyl)-2- (hexahydro-1-methyl-1H-azepin-4-yl)-1(2H)- phthalazinone HCl | Corifina | Loxin | Vividrin akut Azelastin | Optivar | Rhinolast | Optilast | Afluon | A 5610 | A-5610 | Azeptin |
