Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Atropine sulfate
Drug ID BADD_D00190
Description An alkaloid, originally from Atropa belladonna, but found in other plants, mainly solanaceae.
Indications and Usage For the treatment of poisoning by susceptible organophosphorous nerve agents having anti-cholinesterase activity (cholinesterase inhibitors) as well as organophosphorous or carbamate insecticides.
Marketing Status Prescription; Discontinued
ATC Code A03BA01; S01FA01
DrugBank ID DB00572
KEGG ID D02069
MeSH ID D001285
PubChem ID 60196398
TTD Drug ID D0RG3O
NDC Product Code 51662-1509; 51662-1527; 0404-9823; 0404-9822; 13985-606; 52584-630; 0409-1630; 51552-1391; 0641-6006; 50268-118; 71872-7100; 70518-3120; 38779-2267; 71872-7037; 52584-002; 76329-3340; 51662-1339; 50090-4524; 51662-1311; 0404-9820; 52584-401; 63323-580; 50090-5924; 16729-512; 0409-4910; 50090-3138; 0409-4911; 16729-483; 52584-910; 0404-9821; 71872-7255; 0404-9824; 52584-029; 13371-387; 63827-1014; 71872-7002; 69205-736; 71872-7001; 71872-7245; 0517-1010; 0641-6251; 0404-9819; 16729-484; 76329-3339; 0409-9630; 16729-526; 43235-0004; 51662-1378; 51662-1289; 50090-3104; 52584-044; 51662-1207; 12714-031; 42385-736; 17478-215; 71684-0303; 70121-1705; 0517-0401; 62991-2842; 60505-6226; 62068-306; 52221-107; 55742-124; 76003-0157; 51662-1208; 71872-7246; 69205-031; 16729-525; 71872-7017; 0065-0303; 71872-7252; 24208-825; 51927-0156
Synonyms Atropine | Atropinol | Atropine Sulfate | Sulfate, Atropine | Atropine Sulfate Anhydrous | Anhydrous, Atropine Sulfate | Sulfate Anhydrous, Atropine | AtroPen | Atropin Augenöl | Augenöl, Atropin
Chemical Information
Molecular Formula C34H48N2O10S
CAS Registry Number 55-48-1
SMILES CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3.CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3.OS(= O)(=O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Atrial fibrillationNot AvailableF1PE02Not AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Vision blurred17.17.01.010; 06.02.06.007--
Visual acuity reduced06.02.03.001; 17.17.01.011--
Vomiting07.01.07.003--
Withdrawal syndrome19.07.02.005; 08.06.02.012--Not Available
Peripheral pulse decreased13.14.04.014--Not Available
Electrocardiogram R on T phenomenon13.14.05.008--Not Available
Electrocardiogram P wave abnormal13.14.05.010--Not Available
Eyelid margin crusting23.03.03.029; 06.04.04.005--Not Available
Electrocardiogram repolarisation abnormality13.14.05.011--Not Available
Neurological examination abnormal13.15.01.009--Not Available
Trigeminal nerve disorder17.04.08.004--
Feeding disorder19.09.01.003; 14.03.02.003--Not Available
Mental disorder19.07.01.002--Not Available
Poisoning12.03.01.004--Not Available
Abnormal behaviour19.01.01.001--Not Available
Erectile dysfunction19.08.04.001; 21.03.01.007--
Oral disorder07.05.01.005--Not Available
Gastrointestinal sounds abnormal07.01.01.002--Not Available
Use of accessory respiratory muscles22.02.08.017--Not Available
Atrioventricular dissociation02.03.01.012--Not Available
Sinus node dysfunction02.03.03.017--
Locomotive syndrome17.02.05.045; 15.03.01.019--Not Available
Adverse food reaction08.06.01.025--Not Available
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