Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Articaine hydrochloride
Drug ID BADD_D00170
Description Articaine is a dental local anesthetic. Articaine is widely used around the world and is the most popular local anesthetic in many European countries.
Indications and Usage
Marketing Status Not Available
ATC Code N01BB08
DrugBank ID DB09009
KEGG ID D02991
MeSH ID D002355
PubChem ID 32169
TTD Drug ID D0I5HV
NDC Product Code 68108-0610; 65675-1004; 53335-0001
Synonyms Carticaine | Carticain | Articain | Articaine | Carticaine Hydrochloride | Hydrochloride, Carticaine | Hoe-40045 | Hoe 40045 | Hoe40045 | Hoe-045 | Hoe 045 | Hoe045 | Ultracaine
Chemical Information
Molecular Formula C13H21ClN2O3S
CAS Registry Number 161448-79-9
SMILES CCCNC(C)C(=O)NC1=C(SC=C1C)C(=O)OC.Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Injection site pain12.07.03.011; 08.02.03.010--Not Available
Injury12.01.08.004--Not Available
Loss of consciousness17.02.04.004--Not Available
Lymphadenopathy01.09.01.002--Not Available
Malaise08.01.01.003--
Migraine24.03.05.003; 17.14.02.001--Not Available
Mouth ulceration07.05.06.004--Not Available
Myalgia15.05.02.001--
Nausea07.01.07.001--
Neck pain15.03.04.009--
Nervousness19.06.02.003--Not Available
Neuropathy peripheral17.09.03.003--Not Available
Oedema14.05.06.010; 08.01.07.006--Not Available
Osteomyelitis15.02.05.001; 11.01.01.001--
Otitis media11.01.05.004; 04.05.01.001--
Pain08.01.08.004--
Palpitations02.01.02.003--
Paraesthesia17.02.06.005--
Pharyngitis22.07.03.004; 11.01.13.003; 07.05.07.004--
Pruritus23.03.12.001--
Rhinitis22.07.03.006; 11.01.13.004--
Salivary hypersecretion07.06.01.009--Not Available
Sensory loss17.02.07.007--Not Available
Shock24.06.02.002--Not Available
Sinus congestion22.04.06.001--Not Available
Sinus headache22.02.05.023; 17.14.01.002--
Skin disorder23.03.03.007--Not Available
Somnolence17.02.04.006; 19.02.05.003--
Stomatitis07.05.06.005--
Swelling08.01.03.015--Not Available
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