| Drug Name |
Argatroban |
| Drug ID |
BADD_D00161 |
| Description |
Argatroban is a direct, selective thrombin inhibitor. The American College of Cardiologists (ACC) recommend using bivalirudin or argatroban in patients who have had, or at risk for, heparin induced thrombocytopenia (HIT) and are undergoing percutaneous coronary intervention. Argatroban is a non-heparin anticoagulant shown to both normalize platelet count in patients with HIT and prevent the formation of thrombi. Parental anticoagulants must be stopped and a baseline activated partial thromboplastin time must be obtained prior to administering argatroban. |
| Indications and Usage |
Argatroban is indicated for prevention and treatment of thrombosis caused by heparin induced thrombocytopenia (HIT). It is also indicated for use in patients with, or at risk for, HIT who are undergoing percutaneous coronary intervention. |
| Marketing Status |
Prescription; Discontinued |
| ATC Code |
B01AE03 |
| DrugBank ID |
DB00278
|
| KEGG ID |
C04931
|
| MeSH ID |
C031942
|
| PubChem ID |
92722
|
| TTD Drug ID |
D07UWV
|
| NDC Product Code |
0078-0930; 68083-141; 0143-9288; 65145-126; 16729-430; 65219-429; 0409-1140; 55150-241; 70121-1037; 63323-526; 0143-9674; 25021-414; 0143-9377; 42023-182; 67457-212; 55486-1582; 76339-118; 45562-1124; 70333-1191; 0143-9559; 62227-015 |
| Synonyms |
argatroban | MPQA | (2R,4R)-1-(5-((aminoiminomethyl)amino)-1-oxo-2-(((1,2,3,4-tetrahydro-3-methyl-8-quinolinyl)sulfonyl)amino)pentyl)-4-methyl-2-piperidinecarboxylic acid monohydrate | MMTQAP | argatroban monohydrate | argatroban hydrate | Acova | (21R)-argatroban anhydrous | (2R,4R)-1-((2S)-5-((aminoiminomethyl)amino)-1-oxo-2-((((3R)-1,2,3,4-tetrahydro-3-methyl-8-quinolinyl)sulfonyl)amino)pentyl)-4-methyl-2-piperidinecarboxylic acid | (21S)-argatroban anhydrous | (2R,4R)-1-((2S)-5-((aminoiminomethyl)amino)-1-oxo-2-((((3S)-1,2,3,4-tetrahydro-3-methyl-8-quinolinyl)sulfonyl)amino)pentyl)-4-methyl-2-piperidinecarboxylic acid | (21S)-argatroban | (21R)-argatroban | MD 805 | MD805 | MD-805 | Novastan | argatroban anhydrous | (2R,4R)-1-(5-((aminoiminomethyl)amino)-1-oxo-2-(((1,2,3,4-tetrahydro-3-methyl-8-quinolinyl)sulfonyl)amino)pentyl)-4-methyl-2-piperidinecarboxylic acid | MCI 9038 | MCI-9038 |
