| Drug Name |
Amphetamine |
| Drug ID |
BADD_D00130 |
| Description |
Amphetamine, a compound discovered over 100 years ago, is one of the more restricted controlled drugs. It was previously used for a large variety of conditions and this changed until this point where its use is highly restricted. Amphetamine, with the chemical formula alpha-methylphenethylamine, was discovered in 1910 and first synthesized by 1927. After being proven to reduce drug-induced anesthesia and produce arousal and insomnia, amphetamine racemic mix was registered by Smith, Kline and French in 1935. Amphetamine structure presents one chiral center and it exists in the form of dextro- and levo-isomers.[A18540] The first product of Smith, Kline and French was approved by the FDA on 1976.[L5194]
During World War II, amphetamine was used to promote wakefulness in the soldiers. This use derived into a large overproduction of amphetamine and all the surplus after the war finalized ended up in the black market, producing the initiation of the illicit abuse.[A18540] |
| Indications and Usage |
For treatment of Attention Deficit Disorder with Hyperactivity (ADDH), narcolepsy, and exogenous obesity as a short term (a few weeks) adjunct in a regimen of weight reduction based on caloric restriction for patients refractory to alternative therapy. |
| Marketing Status |
Prescription; Discontinued |
| ATC Code |
N06BA01 |
| DrugBank ID |
DB00182
|
| KEGG ID |
D07445
|
| MeSH ID |
D000661
|
| PubChem ID |
3007
|
| TTD Drug ID |
D05BMG
|
| NDC Product Code |
70165-005; 70165-025; 70165-015; 27808-109; 27808-108; 27808-102; 70165-030; 69452-227; 69452-228; 70165-010; 69238-1563; 69238-1564; 27808-106; 70165-020; 27808-110 |
| Synonyms |
Amphetamine | Amfetamine | Phenopromin | Desoxynorephedrin | Phenamine | Centramina | Fenamine | Mydrial | Thyramine | Amphetamine Sulfate | Sulfate, Amphetamine | Amphetamine Sulfate (2:1) | l-Amphetamine | l Amphetamine | levo-Amphetamine | levo Amphetamine | Levoamphetamine |
