Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Almotriptan malate
Drug ID BADD_D00078
Description Almotriptan is a triptan drug for the treatment of migraine headaches. Almotriptan is in a class of medications called selective serotonin receptor agonists. It works by narrowing blood vessels in the brain, stopping pain signals from being sent to the brain, and stopping the release of certain natural substances that cause pain, nausea, and other symptoms of migraine. Almotriptan does not prevent migraine attacks.
Indications and Usage For the treatment of acute migraine headache in adults
Marketing Status approved; investigational
ATC Code N02CC05
DrugBank ID DB00918
KEGG ID D02825
MeSH ID C409045
PubChem ID 123607
TTD Drug ID D0P0SM
NDC Product Code 14501-0073; 0093-5260; 0093-5261; 65015-673; 67835-5003
UNII PJP312605E
Synonyms almotriptan | almotriptan malate | Axert | Almogran
Chemical Information
Molecular Formula C21H31N3O7S
CAS Registry Number 181183-52-8
SMILES CN(C)CCC1=CNC2=C1C=C(C=C2)CS(=O)(=O)N3CCCC3.C(C(C(=O)O)O)C(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001---
Abdominal pain07.01.05.002--
Abdominal pain upper07.01.05.003--
Abnormal dreams19.02.03.001; 17.15.02.001---
Acute myocardial infarction24.04.04.001; 02.02.02.001---
Anaphylactic reaction10.01.07.001; 24.06.03.006--
Anaphylactic shock24.06.02.004; 10.01.07.002---
Angina pectoris24.04.04.002; 02.02.02.002--
Angioedema22.04.02.008; 23.04.01.001; 10.01.05.009---
Anxiety19.06.02.002--
Arteriospasm coronary12.02.01.031; 24.04.04.005; 02.02.02.005---
Arthralgia15.01.02.001--
Arthritis15.01.01.001--
Asthenia08.01.01.001---
Back pain15.03.04.005--
Blepharospasm17.17.02.001; 06.05.01.001---
Blood creatine phosphokinase increased13.04.01.001--
Breast pain21.05.05.003--
Bronchitis22.07.01.001; 11.01.09.001--
Chest pain22.12.02.003; 08.01.08.002; 02.02.02.011---
Chills15.05.03.016; 08.01.09.001--
Cold sweat08.01.03.024; 23.02.03.002---
Colitis07.08.01.001--
Confusional state19.13.01.001; 17.02.03.005--
Conjunctivitis11.01.06.012; 06.04.01.002--
Coordination abnormal17.02.02.004---
Depression19.15.01.001--
Dermatitis23.03.04.002---
Diarrhoea07.02.01.001--
Diplopia17.17.01.005; 06.02.06.002---
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