Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Alendronic acid
Drug ID BADD_D00066
Description Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label][A959].
Indications and Usage For the treatment and prevention of osteoporosis in women and Paget's disease of bone in both men and women.
Marketing Status Prescription; Discontinued
ATC Code M05BA04
DrugBank ID DB00630
KEGG ID D07119
MeSH ID D019386
PubChem ID 2088
TTD Drug ID D09KLR
NDC Product Code Not Available
Synonyms Alendronate | 4-Amino-1-Hydroxybutylidene 1,1-Biphosphonate | Aminohydroxybutane Bisphosphonate | MK-217 | MK 217 | MK217 | Alendronate Monosodium Salt, Trihydrate | Alendronate Sodium | Fosamax
Chemical Information
Molecular Formula C4H13NO7P2
CAS Registry Number 66376-36-1
SMILES C(CC(O)(P(=O)(O)O)P(=O)(O)O)CN
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Lung hyperinflation22.02.04.0110.000202%Not Available
Renal cyst haemorrhage24.07.07.003; 20.01.04.017; 16.27.01.0050.000202%Not Available
Tongue injury12.01.09.020; 07.14.01.0160.000404%Not Available
Anticoagulation drug level below therapeutic13.17.01.0190.000303%Not Available
Type V hyperlipidaemia14.08.02.002; 03.08.08.0020.000909%Not Available
Iliotibial band syndrome15.07.02.006; 12.01.07.0130.001516%Not Available
Appendix disorder07.11.01.0200.003435%Not Available
Arterial haemorrhage24.07.01.0630.000202%Not Available
Arterial stenosis24.04.02.0120.000202%Not Available
Escherichia infection11.02.10.0040.000303%Not Available
Foot deformity15.10.03.0050.004850%Not Available
Hip deformity15.10.03.0080.000505%Not Available
Ligament disorder15.07.02.0020.000404%Not Available
Malocclusion07.09.05.0130.000303%Not Available
Mastoid disorder04.05.05.0020.000505%Not Available
Facial nerve disorder17.04.03.0060.000202%
Aortic valve disease02.07.03.0020.000303%
Deformity08.01.03.0220.000404%Not Available
Carotid artery disease24.03.05.009; 17.08.02.0160.000909%Not Available
Nerve root compression17.10.01.0160.000303%Not Available
Purulence11.01.08.0600.000606%Not Available
Vitamin D increased13.02.05.0140.000202%Not Available
Urinary tract infection pseudomonal11.02.12.007; 20.08.02.0130.000202%Not Available
Spider vein24.10.04.003; 23.06.03.0060.000202%Not Available
Low turnover osteopathy20.01.01.010; 15.02.03.016; 14.04.04.0150.018898%Not Available
Spondylolisthesis15.10.04.0040.004446%Not Available
Bone fragmentation12.04.02.013; 15.08.02.0110.000404%Not Available
Human papilloma virus test positive13.08.03.0270.000202%Not Available
Periodic limb movement disorder19.02.05.009; 17.15.04.006; 15.05.03.0340.000202%Not Available
Oroantral fistula22.04.06.005; 07.11.05.0150.000202%Not Available
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