Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Alendronic acid
Drug ID BADD_D00066
Description Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label][A959].
Indications and Usage For the treatment and prevention of osteoporosis in women and Paget's disease of bone in both men and women.
Marketing Status Prescription; Discontinued
ATC Code M05BA04
DrugBank ID DB00630
KEGG ID D07119
MeSH ID D019386
PubChem ID 2088
TTD Drug ID D09KLR
NDC Product Code Not Available
Synonyms Alendronate | 4-Amino-1-Hydroxybutylidene 1,1-Biphosphonate | Aminohydroxybutane Bisphosphonate | MK-217 | MK 217 | MK217 | Alendronate Monosodium Salt, Trihydrate | Alendronate Sodium | Fosamax
Chemical Information
Molecular Formula C4H13NO7P2
CAS Registry Number 66376-36-1
SMILES C(CC(O)(P(=O)(O)O)P(=O)(O)O)CN
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Fungal infection11.03.05.0010.002324%Not Available
Fungal skin infection11.03.05.002; 23.09.02.0010.000404%Not Available
Furuncle23.09.01.004; 11.02.05.0080.000303%Not Available
Gait disturbance17.02.05.016; 08.01.02.0020.007780%
Gallbladder disorder09.03.02.0010.003233%Not Available
Gastric cancer16.13.03.001; 07.21.02.0010.000105%Not Available
Gastric haemorrhage07.12.01.001; 24.07.02.0070.000505%
Gastric polyps07.20.01.003; 16.05.03.0010.000606%Not Available
Gastric ulcer07.04.03.0020.001414%
Gastritis07.08.02.0010.006062%
Gastritis erosive07.04.03.0030.000808%Not Available
Gastritis haemorrhagic24.07.02.008; 07.08.02.0020.000202%Not Available
Gastrooesophageal reflux disease07.02.02.0030.029199%
Gastroenteritis11.01.07.004; 07.19.03.0010.000707%Not Available
Gastroenteritis viral11.05.04.005; 07.19.03.0050.000505%Not Available
Gastrointestinal disorder07.11.01.0010.004243%Not Available
Gastrointestinal haemorrhage24.07.02.009; 07.12.02.001--Not Available
Gastrointestinal pain07.01.05.005--
Generalised anxiety disorder19.06.01.0040.000202%Not Available
Generalised oedema14.05.06.007; 08.01.07.004--
Genital herpes21.10.03.008; 11.05.02.0120.000202%Not Available
Giardiasis07.19.01.015; 11.06.06.0010.000202%Not Available
Gingival bleeding24.07.02.010; 07.09.07.0010.002728%Not Available
Gingival disorder07.09.03.0010.003637%Not Available
Gingival pain07.09.04.0010.000808%
Gingival recession07.09.03.0070.001313%Not Available
Gingival swelling07.05.04.0030.000505%Not Available
Gingivitis11.01.04.013; 07.09.03.0030.002728%
Glaucoma06.03.01.0020.003940%
Glomerulonephritis20.05.01.001; 10.02.01.0060.000202%Not Available
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