Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Alcaftadine
Drug ID BADD_D00058
Description Alcaftadine is a H1 histamine receptor antagonist indicated for the prevention of itching associated with allergic conjunctivitis. This drug was approved in July 2010.
Indications and Usage For the prevention of itching associated with allergic conjunctivitis.
Marketing Status Prescription
ATC Code S01GX11
DrugBank ID DB06766
KEGG ID D06552
MeSH ID C557708
PubChem ID 19371515
TTD Drug ID D0O7JW
NDC Product Code 12502-5263; 0023-4291; 14501-0020; 0023-4290; 42973-204
Synonyms alcaftadine
Chemical Information
Molecular Formula C19H21N3O
CAS Registry Number 147084-10-4
SMILES CN1CCC(=C2C3=CC=CC=C3CCN4C2=NC=C4C=O)CC1
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Ocular hyperaemia06.04.05.0040.291430%Not Available
Pain08.01.08.004--
Periorbital oedema23.04.01.002; 10.01.05.010; 06.08.03.0170.009714%
Photophobia17.17.02.006; 06.01.01.0040.019429%
Somnolence19.02.05.003; 17.02.04.0060.014571%
Swelling face10.01.05.018; 23.04.01.0180.019429%Not Available
Vision blurred17.17.01.010; 06.02.06.0070.034000%
Visual acuity reduced06.02.03.001; 17.17.01.0110.014571%
Foreign body sensation in eyes06.01.01.0060.009714%Not Available
Conjunctival hyperaemia06.04.01.0040.029143%Not Available
Eye pruritus06.04.05.0060.097143%Not Available
Scleral hyperaemia06.04.07.0030.077715%Not Available
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